anti-SH3 Domain Containing Ring Finger 1 (SH3RF1) Antibodies

SH3RF1 encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Additionally we are shipping SH3RF1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SH3RF1 57630 Q7Z6J0
SH3RF1 59009 Q69ZI1
SH3RF1 306417 Q71F54
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Top anti-SH3RF1 Antibodies at antibodies-online.com

Showing 10 out of 33 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SH3RF1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: DU145 cell lysate 100 μL Log in to see 2 to 3 Days
$319.00
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Mouse Un-conjugated ELISA, WB SH3MD2 monoclonal antibody (M01), clone 3H3 Western Blot analysis of SH3MD2 expression in HeLa . Detection limit for recombinant GST tagged SH3MD2 is approximately 0.03ng/ml as a capture antibody. 100 μg Log in to see 11 to 12 Days
$440.00
Details
Human Mouse Un-conjugated ELISA, WB 100 μg Log in to see 11 to 14 Days
$537.17
Details
Human Rabbit Un-conjugated ICC, IF Immunocytochemistry/Immunofluorescence: SH3MD2 Antibody - Staining of human cell line U-2 OS shows localization to intermediate filaments & vesicles. 100 μL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated WB SH3RF1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 9 to 11 Days
$473.93
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: SH3MD2 Antibody [NBP2-20347] - Immunohistochemical analysis of paraffin-embedded Normal Colon, using antibody at 1:250 dilution. Western Blot: SH3MD2 Antibody [NBP2-20347] - Sample (30 ug of whole cell lysate) A: U87-MG 5% SDS PAGE gel, diluted at 1:1000. 0.1 mL Log in to see 8 to 11 Days
$516.98
Details
Human Rabbit Un-conjugated WB Western Blot: SH3MD2 Antibody [NBP1-54972] - Titration: 0.2-1 ug/ml, Positive Control: DU145 cell lysate. 20 μL Log in to see 8 to 11 Days
$233.06
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37 KDa) . 50 μL Log in to see 11 to 12 Days
$305.71
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$416.90
Details

Top referenced anti-SH3RF1 Antibodies

  1. Human Polyclonal SH3RF1 Primary Antibody for ELISA, WB - ABIN566141 : Wilhelm, Xu, Kukekov, Gire, Greene: Proapoptotic Nix activates the JNK pathway by interacting with POSH and mediates death in a Parkinson disease model. in The Journal of biological chemistry 2007 (PubMed)

  2. Human Monoclonal SH3RF1 Primary Antibody for ELISA, WB - ABIN566142 : Wilhelm, Kukekov, Schmit, Biagas, Sproul, Gire, Maes, Xu, Greene: Sh3rf2/POSHER protein promotes cell survival by ring-mediated proteasomal degradation of the c-Jun N-terminal kinase scaffold POSH (Plenty of SH3s) protein. in The Journal of biological chemistry 2012 (PubMed)

More Antibodies against SH3RF1 Interaction Partners

Horse (Equine) SH3 Domain Containing Ring Finger 1 (SH3RF1) interaction partners

  1. A non-significant decrease in SH3RF1 gene expression following the training periods was observed

Xenopus laevis SH3 Domain Containing Ring Finger 1 (SH3RF1) interaction partners

  1. the active JNK signaling complex formed of POSH and the JNK module is essential for the expression of anterior neural genes and apoptosis in anterior development

Human SH3 Domain Containing Ring Finger 1 (SH3RF1) interaction partners

  1. These results show that POSH plays a critical role in the progression of epileptic seizures via N-methyl-D-aspartate receptor trafficking

  2. Data show that the two N-terminal SH3 domains of SH3 domain containing ring finger 1 (SH3RF1) protein interact with FAT1 protein.

  3. We found a genome-wide significant association for rs2282987 in CDK6 and a consistent association for rs2706748 in SH3RF1 .

  4. The data presented here define POSH and Siah2 as important mediators of death receptor mediated apoptosis and suggest targeting the interaction of these two E3 ligases is a promising novel cancer therapeutic strategy.

  5. POSH promotes cell survival in Drosophila and in human rheumatoid arthritis synovial fibroblasts

  6. POSH disassociates from the JNK complex after phosphorylation of MLK3 by Akt2, which leads to down-regulation of the JNK signaling pathway

  7. A previously undescribed step in HIV biogenesis that suggests a direct function for hPOSH-mediated ubiquitination in protein sorting at the trans-Golgi network.

  8. Results identified ALIX as an ubiquitination substrate of POSH and indicate that POSH and ALIX cooperate to facilitate efficient virus release.

  9. POSH inhibits ROMK channels by enhancing dynamin-dependent and clathrin-independent endocytosis and by stimulating ubiquitination of ROMK channels.

  10. This publication pertains to studies in mice.

Mouse (Murine) SH3 Domain Containing Ring Finger 1 (SH3RF1) interaction partners

  1. The pro-apoptotic JNK scaffold protein POSH mediates CHMP2BIntron5-associated toxicity in animal models of frontotemporal dementia.

  2. this study shows that POSH is essential for the integration of cell-type-specific signals that regulate the differentiation, survival, and function of T cells

  3. identify plenty of SH3 (POSH) and JNK-interacting protein 1 (JIP-1) as a multiprotein scaffold network for TCR-mediated JNK1 activation in CD8(+) T cells.

  4. a mechanism by which POSH regulates the localization of activated Rac1 and F-actin assembly to control PCDLP formation and subsequent somal translocation of migratory neurons.

  5. An intracellular signaling pathway for process outgrowth inhibition by Nogo66 implicates the POSH complex as a therapeutic target to enhance axon outgrowth and plasticity in the injured central nervous system.

  6. Siah1 is a binding partner for POSH (plenty of SH3s), a scaffold component of the apoptotic JNK pathway

  7. POSH and JIPs directly associate with one another to form a multiprotein complex, PJAC (POSH-JIP apoptotic complex), that includes all of the known kinase components of the pathway.

  8. Results suggest that the molecular scaffold protein POSH assembles an inhibitory complex that links to the actin-myosin network to regulate neuronal process outgrowth.

SH3RF1 Antigen Profile

Protein Summary

This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module.

Gene names and symbols associated with SH3RF1

  • SH3 domain containing ring finger 1 (SH3RF1) antibody
  • SH3 domain containing ring finger 1 (sh3rf1) antibody
  • SH3 domain containing ring finger 1 S homeolog (sh3rf1.S) antibody
  • SH3 domain containing ring finger 1 (Sh3rf1) antibody
  • 2200003J05Rik antibody
  • MGC135632 antibody
  • MGC189605 antibody
  • Posh antibody
  • R75531 antibody
  • RNF142 antibody
  • Sh3md2 antibody
  • si:ch211-114c9.2 antibody
  • si:dkey-15j16.4 antibody
  • wu:fi42f11 antibody
  • xPOSH antibody

Protein level used designations for SH3RF1

SH3 multiple domains 2 , SH3 domain containing ring finger 1 , putative E3 ubiquitin-protein ligase SH3RF1 , plenty of SH3s , SH3 domain-containing RING finger protein 1 , E3 ubiquitin-protein ligase SH3RF1 , xPOSH , SH3 multiple domains protein 2 , plenty of SH3 domains , ring finger protein 142 , putative scaffolding protein POSH , fi42f11

GENE ID SPECIES
422434 Gallus gallus
461598 Pan troglodytes
548727 Xenopus (Silurana) tropicalis
612744 Canis lupus familiaris
694082 Macaca mulatta
100015104 Monodelphis domestica
100061339 Equus caballus
100222250 Taeniopygia guttata
100354589 Oryctolagus cuniculus
431855 Xenopus laevis
57630 Homo sapiens
528315 Bos taurus
59009 Mus musculus
306417 Rattus norvegicus
100172363 Pongo abelii
556523 Danio rerio
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