SPO11 Proteins

Protein Summary

Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described.

Gene names and symbols associated with SPO11

• Meiotic recombination protein spo-11 (spo-11) antibody
• SPO11, initiator of meiotic double stranded breaks (SPO11) antibody
• SPO11, initiator of meiotic double stranded breaks (Spo11) antibody
• SPO11 meiotic protein covalently bound to DSB (spo11) antibody
• SPO11 meiotic protein covalently bound to DSB (Spo11) antibody

• AI449549 antibody
• CT35 antibody
• SPATA43 antibody
• TOPVIA antibody
• zgc:77876 antibody

Protein level used designations for SPO11

SPO11 meiotic protein covalently bound to DSB homolog , cancer/testis antigen 35 , meiotic recombination protein SPO11 , spermatogenesis associated 43 , sporulation protein, meiosis-specific, SPO11 homolog , sporulation protein, meiosis-specific, SPO11 , sporulation protein, meiosis-specific, SPO11 homolog (S. cervisiae)