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The secreted protein encoded by SEMG2 is involved in the formation of a gel matrix that encases ejaculated spermatozoa. Additionally we are shipping SEMG2 Antibodies (38) and SEMG2 Proteins (3) and many more products for this protein.
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Peptides released by physiological cleavage of Semg1 and Semg2 form amyloids that enhance HIV infection.
These results suggest the involvement of semenogelins in prostate cancer and their prognostic values in predicting cancer progression after radical prostatectomy.
SgII transcripts were demonstrated in several tissues, with the strongest signals coming from seminal vesicles, vas deferens, prostate, epididymis and trachea.
Seminal plasma motility inhibitor, one of the fragments of Sg, has its inhibitory effect on ejaculated spermatozoa in liquefied semen under physiological conditions.
structural changes in the semenogelin 1 and 2 proteins that have arisen since the human-chimpanzee-gorilla split may be responsible for the physiological differences between these species ejaculated semen that correlate with their sociosexual behavior
The binding of Zn2+ to SgI and SgII and their involvment in regulating the activity of PSA are reported.
SGII is a novel target for protein S-nitrosylation in spermatozoa.
semenogelins I and II were directly cleaved by KLK14. Semenogelins were also able to reverse KLK14 inhibition by Zn2+, providing a novel regulatory mechanism for KLK14 activity.
antibacterial activity of the semenogelin-derived peptides generated in seminal plasma was strictly zinc-dependent both at neutral and low pH
Semenogelins (Sgs) modifies the membrane structure, indirectly inhibiting motility, and provides suggestions for a therapy for male infertility through selection of a functional sperm population using Sgs.
Report the gene duplication of SVS III in both mouse and rat.
The secreted protein encoded by this gene is involved in the formation of a gel matrix that encases ejaculated spermatozoa. Proteolysis by the prostate-specific antigen (PSA) breaks down the gel matrix and allows the spermatozoa to move more freely. The encoded protein is found in lesser abundance than a similar semenogelin protein. The genes encoding these two semenogelin proteins are found in a cluster on chromosome 20.
, SVS III
, semenogelin II
, seminal vesicle protein 3
, seminal vesicle secretion 3
, seminal vesicle secretion 3 alpha
, seminal vesicle secretion 3A
, semenogelin 2
, androgen-responsive protein pSv-1
, seminal vesicle secretory protein 3A