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SEPT9 is a member of the septin family involved in cytokinesis and cell cycle control. Additionally we are shipping Septin 9 Proteins (7) and Septin 9 Kits (2) and many more products for this protein.
Showing 10 out of 36 products:
Human Polyclonal SEPT9 Primary Antibody for ELISA, WB - ABIN564709
Tóth, Galamb, Spisák, Wichmann, Sipos, Valcz, Leiszter, Molnár, Tulassay: The influence of methylated septin 9 gene on RNA and protein level in colorectal cancer. in Pathology oncology research : POR 2011
Cow (Bovine) Polyclonal SEPT9 Primary Antibody for WB - ABIN2784607
Sudo, Ito, Iwamoto, Morishita, Asano, Nagata: SEPT9 sequence alternations causing hereditary neuralgic amyotrophy are associated with altered interactions with SEPT4/SEPT11 and resistance to Rho/Rhotekin-signaling. in Human mutation 2007
Thus our data indicate that Sept9_i2 is a negative regulator of breast tumorigenesis. We propose that Sept9 tumorigenic properties depend on the balance between Sept9_i1 and Sept9_i2 expression levels.
The plasma levels of septin-9 and clusterin (show CLU Antibodies) in ovarian cancer patients were abnormally elevated, which might be used as potential candidates of peripheral blood tumor biomarkers for early diagnosis of EOC and septin-9 might be related to distal metastases of EOC.
The primary aim of this study was to evaluate the diagnostic accuracy of a PCR-based assay for the analysis of SEPT9 promoter methylation in circulating cell-free DNA (mSEPT9) for diagnosing hepatocellular carcinoma.
Septin 9 regulates lipid droplet growth through binding to phosphatidylinositol-5-phosphate in Hepatitis C virus infected cells.Septin 9 regulates lipid droplets growth and perinuclear accumulation in a manner dependent on dynamic microtubules.Septin 9 regulates Hepatitis C virus replication.
The SEPT9 assay exhibited satisfactory performance in colorectal cancer diagnosis and screening, while more evidence is needed for therapeutic effect monitoring and prognosis prediction.
Studies indicate that methylated Septin 9 ((m)SEPT9) can be consistently detected in plasma samples derived from whole blood samples collected with S-Monovette(R) K3E and BD Vacutainer (R) K2EDTA tubes stored at 2-8 degrees C for a maximum of 24 h and for samples collected in S-Monovette CPDA tubes stored at 18-25 degrees C for up to 48 h.
our study has validated a new SEPT9 assay and combined testing as an aid in cancer detection, providing a new approach for opportunistic CRC (show CALR Antibodies) screening.
Study shows a stepwise increase of SEPT9 methylation from non-cancerous to cancerous tissue in colorectal adenocarcinoma.
Study found SHOX2 (show SHOX2 Antibodies) and SEPT9 frequently methylated in biliary tract cancers.
The first evidence of an interaction between septins and a nonmitotic kinesin is provided and it is suggested that SEPT9 modulates the interactions of KIF17 (show KIF17 Antibodies) with membrane cargo.
observations suggested that Sept9 contributed to alleviate liver fibrosis might partially through promoting activated HSCs apoptosis and this anti-fibrogenesis effect might be blocked by DNMT (show DNMT1 Antibodies)-3a mediated methylation of Sept9
The altered T-cell homeostasis caused by the loss of Sept9 results in an increase of CD8 (show CD8A Antibodies)(+) central memory T-cells.
SEPT9 gene amplification and overexpression during mouse breast tumorigenesis
Data reveal the importance of Sept9 for septin (show SEPT6 Antibodies) filament formation and general cell stability.
Zebrafish possess two genes, sept9a and sept9b that, like humans, express multiple transcripts.
This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.
, MLL septin-like fusion protein MSF-A
, Ov/Br septin
, ovarian/breast septin
, septin D1
, MLL septin-like fusion
, SL3-3 integration site 1 protein
, eighth septin
, septin-like protein