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SRP68 encodes a subunit of the signal recognition particle (SRP). Additionally we are shipping SRP68 Antibodies (22) and many more products for this protein.
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This multicenter data analysis establishes a six-genotype genetic prognostic model for poor outcomes of papillary thyroid cancer with a risk order of genetic duet of BRAF V600E/RAS mutation and TERT mutation >>>>BRAF V600E = TERT mutation alone >RAS mutation alone = wild-type genes.
Despite a significant prevalence of BRAF (show BRAF Proteins) mutation, more than 70% of hobnail variant of papillary thyroid carcinomas (HPTCs) in our series showed concurrent mutations of other genes such as TP53 (show TP53 Proteins), PIK3CA (show PIK3CA Proteins), CTNNB1 (show CTNNB1 Proteins) and hTERT, in contrast to classic PTC (show F9 Proteins).
Mutational activation of BRAF (show BRAF Proteins) confers sensitivity to TGFBR1 (show TGFBR1 Proteins) inhibitors in human melanoma cells.
miR (show MLXIP Proteins)-579-3p controls melanoma progression and resistance to target therapy by targeting the 3'UTR of two oncoproteins: BRAF (show BRAF Proteins) and MDM2 (show MDM2 Proteins).
Durable (>/=3 years) survival is achievable with dabrafenib plus trametinib in patients with BRAF (show BRAF Proteins) V600-mutant metastatic melanoma
A high extent more than 25% of BRAF (show BRAF Proteins)(V600E) alleles may be associated with disease outcome in PTC (show F9 Proteins) patients.
Study found that high expression of LC3B (show MAP1LC3B Proteins) protein was associated with the presence of BRAF (show BRAF Proteins) V600E mutation and temporal lesion in glioneuronal tumors, as well as in gangliogliomas alone. As for Beclin-1 protein (show BECN1 Proteins), it showed statistically significant correlation with BRAF (show BRAF Proteins) V600E mutation in glioneuronal tumors.
We suggest that BRAF (show BRAF Proteins) mutant patients should not be considered as having a unique biology and provide an in depth characterization of heterogeneous motifs that may be exploited for drug targeting.
The results establish a link between BRAF (show BRAF Proteins)(V600E) and NOX4 (show NOX4 Proteins), which is confirmed by a comparative analysis of NOX4 (show NOX4 Proteins) expression in human (TCGA) and mouse thyroid cancers.
PD-L1 (show CD274 Proteins) expression in colorectal cancer is associated with microsatellite instability and BRAF (show BRAF Proteins) mutations.
This gene encodes a subunit of the signal recognition particle (SRP). The SRP is a ribonucleoprotein complex that transports secreted and membrane proteins to the endoplasmic reticulum for processing. The complex includes a 7S RNA and six protein subunits. The encoded protein is the 68kDa component of the SRP, and forms a heterodimer with the 72kDa subunit that is required for SRP function. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and three pseudogenes of this gene are located within the Smith-Magenis syndrome region on chromosome 17.
94 kDa B-raf protein
, B-Raf proto-oncogene serine/threonine-protein kinase (p94)
, murine sarcoma viral (v-raf) oncogene homolog B1
, proto-oncogene B-Raf
, serine/threonine-protein kinase B-raf
, v-raf murine sarcoma viral oncogene homolog B1
, Signal recognition particle 68kDa
, signal recognition particle 68kDa
, likely ortholog of H. sapiens signal recognition particle 68kDa (SRP68)
, signal recognition particle 68 kDa protein
, signal recognition particle subunit SRP68
, signal recognition particle protein 68
, 68kDA subunit of signal recognition particle
, Signal recognition particle 68 kDa protein