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SRP68 encodes a subunit of the signal recognition particle (SRP). Additionally we are shipping SRP68 Antibodies (21) and many more products for this protein.
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The essential role of the SRP68-SRP72 interaction in the signal recognition particle-mediated protein translocation
The crystal structures of the SRP68 protein-binding domain (PBD) in complex with SRP72-PBD and of the SRP72-RBD (show CACNA1D Proteins) bound to the SRP (show UCN2 Proteins) S domain (SRP (show UCN2 Proteins) RNA, SRP19 (show SRP19 Proteins) and SRP68) detailing all interactions of SRP72 within SRP (show UCN2 Proteins) have been presented.
study presents the crystal structures of the RNA-binding domain of SRP68 (SRP68-RBD (show CACNA1D Proteins)) alone and in complex with SRP (show UCN2 Proteins) RNA and SRP19 (show SRP19 Proteins); data provide the structural basis for eukaryote-specific, SRP68-driven RNA remodeling required for protein translocation
SRP68/72 heterodimers as major nuclear proteins whose binding of histone H4 tail is inhibited by H4R3 methylation.
The RNA binding domain of SRP68 included residues from positions 52 to 252. Ninety-four amino acids near the C terminus of SRP68 mediated the binding to SRP72
This gene encodes a subunit of the signal recognition particle (SRP). The SRP is a ribonucleoprotein complex that transports secreted and membrane proteins to the endoplasmic reticulum for processing. The complex includes a 7S RNA and six protein subunits. The encoded protein is the 68kDa component of the SRP, and forms a heterodimer with the 72kDa subunit that is required for SRP function. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and three pseudogenes of this gene are located within the Smith-Magenis syndrome region on chromosome 17.
Signal recognition particle 68kDa
, signal recognition particle 68kDa
, likely ortholog of H. sapiens signal recognition particle 68kDa (SRP68)
, signal recognition particle 68 kDa protein
, signal recognition particle subunit SRP68
, signal recognition particle protein 68
, 68kDA subunit of signal recognition particle
, Signal recognition particle 68 kDa protein