Signal Recognition Particle 68kDa Proteins (SRP68)

SRP68 encodes a subunit of the signal recognition particle (SRP). Additionally we are shipping SRP68 Antibodies (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SRP68 673 P15056
SRP68 217337 Q8BMA6
Rat SRP68 SRP68 363707  
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Top SRP68 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$8,498.50
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Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$8,498.50
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Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
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SRP68 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Signal Recognition Particle 68kDa (SRP68) Interaction Partners

Human Signal Recognition Particle 68kDa (SRP68) interaction partners

  1. This multicenter data analysis establishes a six-genotype genetic prognostic model for poor outcomes of papillary thyroid cancer with a risk order of genetic duet of BRAF V600E/RAS mutation and TERT mutation >>>>BRAF V600E = TERT mutation alone >RAS mutation alone = wild-type genes.

  2. Despite a significant prevalence of BRAF (show BRAF Proteins) mutation, more than 70% of hobnail variant of papillary thyroid carcinomas (HPTCs) in our series showed concurrent mutations of other genes such as TP53 (show TP53 Proteins), PIK3CA (show PIK3CA Proteins), CTNNB1 (show CTNNB1 Proteins) and hTERT, in contrast to classic PTC (show F9 Proteins).

  3. Mutational activation of BRAF (show BRAF Proteins) confers sensitivity to TGFBR1 (show TGFBR1 Proteins) inhibitors in human melanoma cells.

  4. miR (show MLXIP Proteins)-579-3p controls melanoma progression and resistance to target therapy by targeting the 3'UTR of two oncoproteins: BRAF (show BRAF Proteins) and MDM2 (show MDM2 Proteins).

  5. Durable (>/=3 years) survival is achievable with dabrafenib plus trametinib in patients with BRAF (show BRAF Proteins) V600-mutant metastatic melanoma

  6. A high extent more than 25% of BRAF (show BRAF Proteins)(V600E) alleles may be associated with disease outcome in PTC (show F9 Proteins) patients.

  7. Study found that high expression of LC3B (show MAP1LC3B Proteins) protein was associated with the presence of BRAF (show BRAF Proteins) V600E mutation and temporal lesion in glioneuronal tumors, as well as in gangliogliomas alone. As for Beclin-1 protein (show BECN1 Proteins), it showed statistically significant correlation with BRAF (show BRAF Proteins) V600E mutation in glioneuronal tumors.

  8. We suggest that BRAF (show BRAF Proteins) mutant patients should not be considered as having a unique biology and provide an in depth characterization of heterogeneous motifs that may be exploited for drug targeting.

  9. The results establish a link between BRAF (show BRAF Proteins)(V600E) and NOX4 (show NOX4 Proteins), which is confirmed by a comparative analysis of NOX4 (show NOX4 Proteins) expression in human (TCGA) and mouse thyroid cancers.

  10. PD-L1 (show CD274 Proteins) expression in colorectal cancer is associated with microsatellite instability and BRAF (show BRAF Proteins) mutations.

SRP68 Protein Profile

Protein Summary

This gene encodes a subunit of the signal recognition particle (SRP). The SRP is a ribonucleoprotein complex that transports secreted and membrane proteins to the endoplasmic reticulum for processing. The complex includes a 7S RNA and six protein subunits. The encoded protein is the 68kDa component of the SRP, and forms a heterodimer with the 72kDa subunit that is required for SRP function. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and three pseudogenes of this gene are located within the Smith-Magenis syndrome region on chromosome 17.

Gene names and symbols associated with SRP68

  • B-Raf proto-oncogene, serine/threonine kinase (BRAF)
  • Signal recognition particle 68kDa (GL50803_8916)
  • signal recognition particle 68 (SRP68)
  • signal recognition particle 68 (Srp68)
  • Signal recognition particle protein 68 (Srp68)
  • signal recognition particle 68 (srp68)
  • signal recognition particle 68kDa L homeolog (srp68.L)
  • 2610024I03Rik protein
  • B-RAF1 protein
  • BRAF1 protein
  • CG5064 protein
  • Dmel\\CG5064 protein
  • NS7 protein
  • RAFB1 protein
  • zgc:92573 protein

Protein level used designations for SRP68

94 kDa B-raf protein , B-Raf proto-oncogene serine/threonine-protein kinase (p94) , murine sarcoma viral (v-raf) oncogene homolog B1 , proto-oncogene B-Raf , serine/threonine-protein kinase B-raf , v-raf murine sarcoma viral oncogene homolog B1 , Signal recognition particle 68kDa , signal recognition particle 68kDa , likely ortholog of H. sapiens signal recognition particle 68kDa (SRP68) , signal recognition particle 68 kDa protein , signal recognition particle subunit SRP68 , CG5064-PA , Srp68-PA , signal recognition particle protein 68 , 68kDA subunit of signal recognition particle , Signal recognition particle 68 kDa protein

GENE ID SPECIES
673 Homo sapiens
5700973 Giardia lamblia ATCC 50803
100356249 Oryctolagus cuniculus
100403061 Callithrix jacchus
100540656 Meleagris gallopavo
217337 Mus musculus
363707 Rattus norvegicus
39028 Drosophila melanogaster
446119 Danio rerio
100101323 Xenopus laevis
417363 Gallus gallus
6730 Homo sapiens
403952 Canis lupus familiaris
538777 Bos taurus
100721562 Cavia porcellus
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