Small ArfGAP2 Proteins (SMAP2)

SMAP2 encodes a member of the SPARC family (secreted protein acidic and rich in cysteine/osteonectin/BM-40), which are highly expressed during embryogenesis and wound healing. Additionally we are shipping SMAP2 Antibodies (34) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SMAP2 64094 Q9H3U7
SMAP2 69780 Q7TN29
Rat SMAP2 SMAP2 298500  
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Top SMAP2 Proteins at

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Log in to see Available
Yeast Chicken His tag   1 mg Log in to see 60 to 71 Days
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days

SMAP2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Mouse (Murine)

More Proteins for Small ArfGAP2 (SMAP2) Interaction Partners

Human Small ArfGAP2 (SMAP2) interaction partners

  1. SMOC2 (show SMOC2 Proteins) was highly expressed in both peritoneal and endometrioma lesions. Considering that the genes studied participate either directly or indirectly in cellular processes that can lead to cell migration, angiogenesis, and inappropriate invasion, it is possible that the deregulation of these genes caused the development and maintenance of ectopic tissue.

  2. The expression of Smoc2 (show SMOC2 Proteins) was significantly higher in hepatocellular carcinoma (HCC (show FAM126A Proteins)) tissues compared with corresponding non-tumor liver tissues. Smoc2 (show SMOC2 Proteins) promotes the proliferation of HCC (show FAM126A Proteins) cells through accelerating cell cycle progression.

  3. L1-mediated CRC (show CALR Proteins) progression involves the acquisition of a stem cell-like phenotype, and that SMOC-2 (show SMOC2 Proteins) elevation is necessary for L1-mediated induction of more aggressive/invasive CRC (show CALR Proteins) properties.

  4. SMAP2 (show BRD8 Proteins) immunoprecipitated clathrin and AP-1 (show FOSB Proteins) through a putative clathrin-binding domain and a CALM-binding domain, and SMAP2 (show BRD8 Proteins) mutants that did not interact with clathrin or AP-1 (show FOSB Proteins) could not localize to recycling endosomes

  5. could not detect an association between SMOC2 (show SMOC2 Proteins) gene and AMD (show AMD1 Proteins). This study tests the candidacy of SMOC2 (show SMOC2 Proteins) gene to the etiology of AMD (show AMD1 Proteins)

  6. Results also demonstrated a physical association between SMAP1 (show UNC45A Proteins) and SMAP2 (show BRD8 Proteins), which might serve as a basis for a functional interaction, and identified the intramolecular domains responsible for this association

  7. SMOC2 (show SMOC2 Proteins) SNP may play a role in autoimmune thyroid disease susceptibility as a dominant polymorphism.

  8. mutation in exon 8 of the SMOC2 (show SMOC2 Proteins) gene linked to oligodontia

  9. Homozygosity mapping and candidate prioritization identify mutations, missed by whole-exome sequencing, in SMOC2 (show SMOC2 Proteins), causing major dental developmental defects

  10. In the current study, there were identified sequences in the carboxy-terminal region of SMAP2 that are critical for its specific subcellular localization and its specificity for Arf proteins.

Mouse (Murine) Small ArfGAP2 (SMAP2) interaction partners

  1. either SMAP1 (show SMAP1 Proteins) or SMAP2, is required for proper embryogenesis

  2. study reveals a link between SMAP2 and CALM/syntaxin2 in clathrin-coated vesicle formation from the trans-Golgi network and subsequent acrosome formation

  3. the trans-Golgi network (TGN (show TG Proteins)) was verified as an additional site of SMAP2 localization based on its co-localization with various TGN (show TG Proteins)-marker proteins.

Arabidopsis thaliana Small ArfGAP2 (SMAP2) interaction partners

  1. SMAP2 has an ability to mediate the 2,4-dichlorophenoxyacetic acid response and is expressed only in restricted tissues.

SMAP2 Protein Profile

Protein Summary

This gene encodes a member of the SPARC family (secreted protein acidic and rich in cysteine/osteonectin/BM-40), which are highly expressed during embryogenesis and wound healing. The gene product is a matricellular protein which promotes matrix assembly and can stimulate endothelial cell proliferation and migration, as well as angiogenic activity. Associated with pulmonary function, this secretory gene product contains a Kazal domain, two thymoglobulin type-1 domains, and two EF-hand calcium-binding domains. The encoded protein may serve as a target for controlling angiogenesis in tumor growth and myocardial ischemia. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with Small ArfGAP2 Proteins (SMAP2)

  • SPARC related modular calcium binding 2 (SMOC2)
  • small ArfGAP2 (SMAP2)
  • small ArfGAP 2 (Smap2)
  • small ArfGAP2 (Smap2)
  • small ArfGAP2 S homeolog (smap2.S)
  • small acidic protein 2 (SMAP2)
  • small ArfGAP2 (smap2)
  • 1810031K02Rik protein
  • AA408614 protein
  • bA37D8.1 protein
  • bA270C4A.1 protein
  • dJ421D16.1 protein
  • DTDP1 protein
  • MGC81879 protein
  • MST117 protein
  • MSTP117 protein
  • MSTP140 protein
  • RGD1308418 protein
  • RP1-228H13.3 protein
  • small acidic protein 2 protein
  • Smap1l protein
  • SMAP2 protein

Protein level used designations for Small ArfGAP2 Proteins (SMAP2)

SMAP-2 , SMOC-2 , SPARC-related modular calcium-binding protein 2 , secreted modular calcium-binding protein 2 , smooth muscle associated protein 2 , smooth muscle-associated protein 2 , thyroglobulin type-1 repeat containing protein , stromal membrane-associated GTPase-activating protein 2 , stromal membrane-associated protein 2 , small ArfGAP2

64094 Homo sapiens
64744 Homo sapiens
69780 Mus musculus
298500 Rattus norvegicus
419641 Gallus gallus
444489 Xenopus laevis
456793 Pan troglodytes
482458 Canis lupus familiaris
514465 Bos taurus
694502 Macaca mulatta
822016 Arabidopsis thaliana
100025294 Monodelphis domestica
100068190 Equus caballus
100145888 Sus scrofa
100338826 Oryctolagus cuniculus
100405875 Callithrix jacchus
100434975 Pongo abelii
100476090 Ailuropoda melanoleuca
100557972 Anolis carolinensis
100581081 Nomascus leucogenys
100721107 Cavia porcellus
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