Sperm Acrosome Associated 1 Proteins (SPACA1)

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Additionally we are shipping Sperm Acrosome Associated 1 Antibodies (25) and Sperm Acrosome Associated 1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SPACA1 81833 Q9HBV2
SPACA1 67652 Q9DA48
SPACA1 614884 Q2YDG7
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Top Sperm Acrosome Associated 1 Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,649.05
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,960.83
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,460.33
Details

SPACA1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,
Mouse (Murine)
,
Cow (Bovine)

More Proteins for Sperm Acrosome Associated 1 (SPACA1) Interaction Partners

Human Sperm Acrosome Associated 1 (SPACA1) interaction partners

  1. Spaca1 role in male infertility.Distribution of SPACA1 in the sperm affects the outcomes of conventional in vitro fertilization.

  2. Human posterior head 20 (hPH20) and homo sapiens sperm acrosome associated 1 (hSPACA1) immunocontraceptive epitopes reduced fertility in male/female mice.

  3. SAMP32 was associated with the inner acrosomal membrane and recombinant SAMP32 reacted with serum from an infertile man suggesting that it is isoantigenic

Mouse (Murine) Sperm Acrosome Associated 1 (SPACA1) interaction partners

  1. SPACA1-deficient male mice are infertile with abnormally shaped sperm heads reminiscent of globozoospermia.

Sperm Acrosome Associated 1 (SPACA1) Protein Profile

Protein Summary

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.

Gene names and symbols associated with SPACA1

  • sperm acrosome associated 1 (SPACA1)
  • sperm acrosome associated 1 (Spaca1)
  • 1700124L11Rik protein
  • 4930540L03Rik protein
  • SAMP32 protein

Protein level used designations for SPACA1

sperm acrosomal membrane-associated protein 32 , sperm acrosome membrane-associated protein 1

GENE ID SPECIES
81833 Homo sapiens
67652 Mus musculus
614884 Bos taurus
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