Sperm Acrosome Associated 1 Proteins

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization.

Data Quality
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Type
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    Protein
Antigen
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Reactivity
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  • 2
  • 1
Application
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Host
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Binding Specificity
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Conjugate
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Protein Type
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Format
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6 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3129450
$5,122.60
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 50 to 55 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3087764
$6,570.39
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 50 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3129449
$6,570.39
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 50 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3087763
$7,294.44
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 50 to 55 Business Days
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1321048
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityCow (Bovine)
Application ELISA
Order details Cat. No. ABIN1623102
$2,460.33
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
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Sperm Acrosome Associated 1 (SPACA1) Protein Profile

Protein Summary

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.

Gene names and symbols associated with SPACA1

  • sperm acrosome associated 1 (SPACA1) antibody
  • sperm acrosome associated 1 (Spaca1) antibody
  • 1700124L11Rik antibody
  • 4930540L03Rik antibody
  • SAMP32 antibody

Protein level used designations for SPACA1

sperm acrosomal membrane-associated protein 32 , sperm acrosome membrane-associated protein 1

GENE ID SPECIES
81833 Homo sapiens
67652 Mus musculus
614884 Bos taurus
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