Sperm Acrosome Associated 1 Proteins
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization.
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Sperm Acrosome Associated 1 (SPACA1) (AA 29-305) protein (rho-1D4 tag) Protein
Sperm Acrosome Associated 1 (SPACA1) (AA 30-221) protein (His tag) Protein
Sperm Acrosome Associated 1 (SPACA1) (AA 29-231) protein (His tag) Protein
Sperm Acrosome Associated 1 (SPACA1) (AA 30-294) protein (rho-1D4 tag) Protein
Sperm Acrosome Associated 1 (SPACA1) (AA 1-294) protein (GST tag) Protein
Sperm Acrosome Associated 1 (SPACA1) (AA 30-221) protein (His tag) Protein
Sperm Acrosome Associated 1 (SPACA1) Protein Profile
Protein Summary
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.
Gene names and symbols associated with SPACA1
- sperm acrosome associated 1 (SPACA1) antibody
- sperm acrosome associated 1 (Spaca1) antibody
- 1700124L11Rik antibody
- 4930540L03Rik antibody
- SAMP32 antibody
Protein level used designations for SPACA1
sperm acrosomal membrane-associated protein 32 , sperm acrosome membrane-associated protein 1
| GENE ID | SPECIES |
|---|---|
| 81833 | Homo sapiens |
| 67652 | Mus musculus |
| 614884 | Bos taurus |
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