Protein Summary

RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer- dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site (By similarity). Shows a preference for AGC or AGA (By similarity). {ECO:0000250|UniProtKB:Q8BGJ9}.

Gene names and symbols associated with U2AF1L4

• U2 small nuclear RNA auxiliary factor 1 like 4 (U2AF1L4) antibody
• U2 small nuclear RNA auxiliary factor 1-like 4 (U2af1l4) antibody

• AA407033 antibody
• AF419339 antibody
• AI451269 antibody
• AW553050 antibody
• TMEM149 antibody
• Show all synonym aliases
• U2 small nuclear RNA auxiliary factor 1-like protein 3 antibody
• U2AF1-like 4 antibody
• U2AF1-like protein 3 antibody
• U2AF1-RS3 antibody
• U2AF1L3 antibody
• U2AF1L3V1 antibody
• U2AF1RS3 antibody
• U2af26 antibody

Protein level used designations for U2AF1L4

U2 auxiliary factor 26 , U2 small nuclear RNA auxiliary factor 1-like 3 , U2 small nuclear RNA auxiliary factor 1-like protein 3 , U2 small nuclear RNA auxiliary factor 1-like protein 4 , U2(RNU2) small nuclear RNA auxiliary factor 1-like 3 , U2(RNU2) small nuclear RNA auxiliary factor 1-like protein 3 , U2AF1-like 4 , U2AF1-like protein 3 , splicing factor U2AF 26 kDa subunit , auxiliary factor 26 , Cb2-807 , Liver regeneration-related protein LRRG157/LRRG158 , liver regeneration-related protein LRRG157/LRRG158 , transmembrane protein 149