Spondin 1 Proteins (SPON1)

Cell adhesion protein that promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro. Additionally we are shipping SPON1 Antibodies (66) and SPON1 Kits (10) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SPON1 233744 Q8VCC9
SPON1 10418 Q9HCB6
SPON1 64456 P35446
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Top SPON1 Proteins at antibodies-online.com

Showing 8 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,741.67
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,741.67
Details
Escherichia coli (E. coli) Human His tag 100 μg 15 to 18 Days
$669.00
Details
Escherichia coli (E. coli) Mouse His tag 100 μg 15 to 18 Days
$701.00
Details
Wheat germ Human GST tag 10 μg 11 to 12 Days
$414.29
Details
Escherichia coli (E. coli) Zaire ebolavirus His-SUMO Tag 100 μg 11 Days
$663.30
Details
Yeast Zaire ebolavirus His tag 100 μg 8 to 11 Days
$752.40
Details
Yeast Rat His tag   1 mg 60 to 71 Days
$4,284.50
Details

SPON1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , ,
,
Rat (Rattus)

More Proteins for Spondin 1 (SPON1) Interaction Partners

Mouse (Murine) Spondin 1 (SPON1) interaction partners

  1. Study identified a novel role for the extracellular matrix protein F-spondin in circadian behavior. In the absence of F-spondin, mice lost their ability to maintain typical intrinsic rhythmicity. Moreover, F-spondin loss results in the displacement of vasoactive intestinal peptide (VIP)-expressing neurons, a class of neurons that are essential for maintaining rhythmicity among suprachiasmatic nucleus neurons.

  2. We conclude that upon ligand binding, TLR4 activates PI3K/Akt signaling to induce F-spondin expression, subsequently control CREB-mediated IL-6 production to promote VSMC migration. These findings provide vital insights into the essential role of F-spondin in VSMC function and will be valuable for developing new therapeutic strategies against atherosclerosis.

  3. These findings demonstrated novel roles for F-spondin and IL-1Ra in type B CpG oligodeoxynucleotides-mediated cell proliferation and migration of macrophages.

  4. Spon1 deletion leads to a local and systemic reduction of TGF-beta levels resulting in increased BMP signaling and increased bone deposition in adult mice.

  5. F-spondin is expressed in embryonic cartilage, where it has the capacity to enhance chondrocyte terminal differentiation and mineralization.

Human Spondin 1 (SPON1) interaction partners

  1. SPON1 rs2618516 polymorphism moderated the effects of APOE on working memory in terms of both in behaviors and in the level of brain activations.

  2. gene expression experiment revealed that CYP2B6, SPON1, and GSG1L can be activated concomitantly through a constitutive androstane receptor (CAR) activation pathway

  3. SPON1 promotes metastatic progression through Fak and Src dependent pathway in human osteosarcoma.

  4. These data suggest that SPON1 may be associated with the differential rate of cognitive decline in Alzheimer disease.

  5. High SPON1 expression is associated with high-grade gliomas.

  6. Genome-wide scan of healthy human connectome discovers SPON1 gene variant influencing dementia severity

  7. downregulates osteoclast recruitment to the root side of periodontal tissue via low-density lipoprotein receptor-related protein 8 and inhibits differentiation of osteoclastic precursors

  8. These findings indicate that F-spondin regulates the differentiation of human cementoblast-like cells via BMP7 expression.

  9. The unique feature of F-spondin FS domain is the presence of three disulfide bonds associated with the N- and C-termini of the domain and a highly conserved N-linked glycosylation site.

  10. expression profile of VSGP/F-spondin identifies this molecule as a potential diagnostic marker or target for developing therapeutic strategies to treat ovarian carcinoma

  11. identified F-spondin as a promoting factor for cementoblastic differentiation

  12. The crystal structure of the reelin-N domain resolved to 2.0 A reveals a variant immunoglobulin-like fold and potential heparin-binding sites.

  13. These studies identify F-spondin as a novel protein in osteoarthritis cartilage, where it may act in situ at lesional areas to activate latent TGF-beta and induce cartilage degradation.

Pig (Porcine) Spondin 1 (SPON1) interaction partners

  1. the porcine testis produces F-spondin and production of this protein is evident in the immature porcine testis, but not the adult testis.

SPON1 Protein Profile

Protein Summary

Cell adhesion protein that promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro. May contribute to the growth and guidance of axons in both the spinal cord and the PNS (By similarity).

Gene names and symbols associated with Spondin 1 Proteins (SPON1)

  • spondin 1, (f-spondin) extracellular matrix protein (Spon1)
  • spondin 1 (SPON1)
  • spondin 1 (Spon1)
  • spondin 1, extracellular matrix protein (SPON1)
  • spondin 1, extracellular matrix protein S homeolog (spon1.S)
  • AI666765 protein
  • AW455831 protein
  • BC020531 protein
  • D330035F22Rik protein
  • F-spondin protein
  • FSP protein
  • spon1-A protein
  • Sponf protein
  • VSGP protein
  • VSGP/F-spondin protein

Protein level used designations for Spondin 1 Proteins (SPON1)

F-spondin , spondin-1 , spondin 1, (f-spondin) extracellular matrix protein , vascular smooth muscle cell growth-promoting factor , f-spondin

GENE ID SPECIES
233744 Mus musculus
10418 Homo sapiens
64456 Rattus norvegicus
282866 Bos taurus
395657 Gallus gallus
100127436 Sus scrofa
476864 Canis lupus familiaris
378682 Xenopus laevis
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