Sulfatase Modifying Factor 2 Proteins (SUMF2)

The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly). Additionally we are shipping SUMF2 Antibodies (15) and SUMF2 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SUMF2 25870 Q8NBJ7
SUMF2 67902 Q8BPG6
Rat SUMF2 SUMF2 360800  
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Top SUMF2 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,465.26
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,465.26
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$547.80
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,722.50
Details

SUMF2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Sulfatase Modifying Factor 2 (SUMF2) Interaction Partners

Human Sulfatase Modifying Factor 2 (SUMF2) interaction partners

  1. SUMF2 interacted with IL-13 (show IL13 Proteins) and inhibited IL-13 (show IL13 Proteins) secretion in bronchial smooth muscle cells and lymphocytes, which was independent of IL-13 (show IL13 Proteins) glycosylation

  2. structural analysis of human pFGE by X-ray crystallography [pFGE]

  3. pFGE (SUMF2) is the paralog of the Calpha (show PRKACA Proteins)-formylglycine-generating enzyme

  4. SUMF2 interacts with sulphatase-modifying factor 1 to regulate sulphatase activities.

  5. pFGE is retained in the ER through its C-terminal tetrapeptide PGEL, a noncanonical variant of the classic KDEL ER-retention signal.

SUMF2 Protein Profile

Protein Summary

The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly). The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum. This protein has low levels of FGly-generating activity but can heterodimerize with another family member - a protein with high levels of FGly-generating activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with SUMF2

  • sulfatase modifying factor 2 (SUMF2)
  • sulfatase modifying factor 2 L homeolog (sumf2.L)
  • sulfatase modifying factor 2 (sumf2)
  • sulfatase modifying factor 2 (Sumf2)
  • 2610040F05Rik protein
  • DKFZp468M2113 protein
  • MGC82506 protein
  • pFGE protein
  • sumf2 protein
  • zgc:103574 protein

Protein level used designations for SUMF2

sulfatase modifying factor 2 , sulfatase-modifying factor 2 , Sulfatase-modifying factor 2 , C-alpha-formyglycine-generating enzyme 2 , C-alpha-formylglycine-generating enzyme 2 , paralog of the formylglycine-generating enzyme

GENE ID SPECIES
417542 Gallus gallus
432273 Xenopus laevis
449807 Danio rerio
479701 Canis lupus familiaris
548860 Xenopus (Silurana) tropicalis
742768 Pan troglodytes
100172116 Pongo abelii
100224222 Taeniopygia guttata
25870 Homo sapiens
67902 Mus musculus
360800 Rattus norvegicus
509497 Bos taurus
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