anti-Sulfiredoxin 1 (SRX1) Antibodies

Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Additionally we are shipping Sulfiredoxin 1 Kits (8) and Sulfiredoxin 1 Proteins (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SRX1 140809 Q9BYN0
SRX1 296271  
SRX1 76650 Q9D975
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Top anti-Sulfiredoxin 1 Antibodies at antibodies-online.com

Showing 10 out of 38 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$429.84
Details
Dog Goat Un-conjugated ELISA, WB 100 μg Log in to see 11 to 14 Days
$610.50
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of A549 cells, using SRX1 antibody. ABIN6272872 at 1/100 staining Human lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 Mouse brain lysates probed with Anti SRXN1 Polyclonal Antibody, Unconjugated  at 1:3000 for 90 min at 37˚C. 100 μL Log in to see 3 to 7 Days
$329.45
Details
Human Goat Un-conjugated ELISA, WB Western Blot: SRXN1 Antibody [NBP1-36991] - Analysis of SRXN1 in Human Kidney lysate (35ug protein in RIPA buffer) using this antibody at 0.5ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$488.73
Details
Human Goat Un-conjugated WB   0.1 mg Log in to see 16 Days
$462.00
Details
Human Rabbit Cy5 IF (p)   100 μL Log in to see 14 to 21 Days
$428.45
Details
Human Rabbit Cy5.5 IF (p)   100 μL Log in to see 14 to 21 Days
$428.45
Details
Human Rabbit Cy7 IF (p)   100 μL Log in to see 14 to 21 Days
$428.45
Details
Human Rabbit HRP IHC (p)   100 μL Log in to see 14 to 21 Days
$428.45
Details

Top referenced anti-Sulfiredoxin 1 Antibodies

  1. Human Polyclonal SRX1 Primary Antibody for IF (p), IHC (p) - ABIN1387599 : Zhou, Zhou, Yu, Wu, Chen, Zhao et al.: Sulfiredoxin-1 exerts anti-apoptotic and neuroprotective effects against oxidative stress-induced injury in rat cortical astrocytes following exposure to oxygen-glucose deprivation and hydrogen ... in International journal of molecular medicine 2015 (PubMed)

  2. Human Polyclonal SRX1 Primary Antibody for ELISA, WB - ABIN450073 : Jönsson, Johnson, Lowther: Structure of the sulphiredoxin-peroxiredoxin complex reveals an essential repair embrace. in Nature 2008 (PubMed)

More Antibodies against Sulfiredoxin 1 Interaction Partners

Human Sulfiredoxin 1 (SRX1) interaction partners

  1. NRF2, DJ1 and SRNX1 are commonly expressed in diffusely infiltrating astrocytomas and they can be used in predicting patient prognosis.

  2. Study identify a role for Srxn1 as a denitrosylase for neuronal Prx2. Finding points to the NO/Srxn1 pair in a previously unrecognized redox cycle that modulates Prx2 peroxidase activity.

  3. Wnt/beta-catenin pathway was stimulated by sulfiredoxin in tumor cell line, with activation of CD44-its target genes-resulting in the promotion of invasion and migration in cervical cancer cell lines.

  4. This review will highlight the cumulative effects of sulfiredoxin in various systemic disorders with a strong emphasis on its target activity and the factors influencing its expression in such conditions.

  5. The up-regulated expression of Srx was significantly associated with lymph node metastasis, infiltration of vessels, and the depth of cancer invasion.

  6. The analysis of SXR polymorphism is a promising tool to predict both the favourable response to corticosteroids and the risk of developing steroid resistance

  7. rs6053666 of SRXN1 is associated with cerebrovascular disease in a Finnish cohort

  8. Increased expression of Srx protects peroxiredoxins against hyperoxidation in the early stage of hyperglycaemia.

  9. We silenced Srx by short hairpin RNA in HeLa and SiHa cells. Diminished Srx expression upregulated E-cadherin expression. The cell invasion and migration activity in the ShSrx group were obviously decreased in HeLa and SiHa cells.

  10. Study shows that Srx plays a critical oncogenic role to promote cell invasion and metastasis, which is at least partially due to its stimulation of the MAPK pathway through EGFR deacetylation.

  11. This review will summarize the molecular basis of differences in the affinity of Srx for individual Prx and the role of individual component of the Srx-Prx system in tumor progression and metastasis.

  12. Gemfibrozil, a lipid-lowering drug, increases myelin genes in human oligodendrocytes via peroxisome proliferator-activated receptor-beta.

  13. NRF2 and SRXN1 genetic polymorphisms are associated with breast cancer risk and survival

  14. SRX forms a complex with S100A4 (and has stronger affinity for S-glutathionylated S100A4), regulates its activity, and mediates redox regulation of the interaction of S100A4 with nonmuscle myosin heavy chain II-A.

  15. Smokers and ex-smokers had significantly more sulfiredoxin expression in their tumors and in patients receiving cytostatic drugs or radiation therapy, sulfiredoxin expression predicted a poor prognosis.

  16. Srx functions as a novel component to maintain the balance between H2O2 production and elimination

  17. Real-time PCR validated that up-regulation of sulphiredoxin 1 homolog (SRXN1), hemeoxygenase 1 (HMOX1), and breast carcinoma amplified sequence 3 (BCAS3) were consistently modulated.

  18. Srx-Prx IV axis is critical for lung cancer maintenance and metastasis, suggesting that targeting the Srx-Prx IV axis may provide unique effective strategies for cancer prevention and treatment.

  19. sulfiredoxin 1 is associatd with the pathogenesis of human pulmonary fibrosis.

  20. Studies present the 2.1 A crystal structure of human Srx in complex with PrxI, ATP, and Mg(2+).

Mouse (Murine) Sulfiredoxin 1 (SRX1) interaction partners

  1. sulfiredoxin is degraded by Lon in a manner dependent on PrxIII hyperoxidation state.

  2. Srx is one of the critical components that contribute to mouse skin tumorigenesis in vivo.

  3. data provide in vivo evidence that loss of Srx renders mice resistant to azoxymethane/dextran sulfate sodium-induced colon carcinogenesis, suggesting that Srx has a critical oncogenic role in cancer development

  4. The concerted action of PrxIII and Srx is important for protection against pyrazole-induced oxidative stress arising from the convergent induction of CYP2E1-derived and ER stress-derived ROS in mitochondria.

  5. Srx functions as a novel component to maintain the balance between H2O2 production and elimination

  6. NO-mediated Srx up-regulation is mediated by the transcription factor nuclear factor erythroid 2-related factor (Nrf2) and the NO/Srx pathway inhibits generation of reactive oxygen species.

  7. Sulfiredoxin protects mice from lipopolysaccharide-induced endotoxic shock

  8. LPS-mediated Srx induction is dependent on both AP-1 and Nrf2, which is regulated by Nox2-derived reactive oxygen species.

  9. Synaptic activity upregulated the thioredoxin-peroxiredoxin reactivating gene sulfiredoxin.

Sulfiredoxin 1 (SRX1) Antigen Profile

Protein Summary

Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase.

Gene names and symbols associated with anti-Sulfiredoxin 1 (SRX1) Antibodies

  • sulfiredoxin 1 (SRXN1) antibody
  • sulfiredoxin 1 homolog (S. cerevisiae) (srxn1) antibody
  • sulfiredoxin 1 (Srxn1) antibody
  • sulfiredoxin 1 homolog (S. cerevisiae) (Srxn1) antibody
  • 1700127B04Rik antibody
  • Ab2-390 antibody
  • AI854065 antibody
  • AW488194 antibody
  • C20orf139 antibody
  • Npn3 antibody
  • Srx antibody
  • Srx1 antibody
  • TX01 antibody

Protein level used designations for anti-Sulfiredoxin 1 (SRX1) Antibodies

sulfiredoxin 1 , sulfiredoxin 1 homolog , sulfiredoxin-1 , sulfiredoxin-1-like , sulfiredoxin 1 homolog (S. cerevisiae) , neoplastic progression 3 , neoplastic progression protein 3

GENE ID SPECIES
469853 Pan troglodytes
714997 Macaca mulatta
100331561 Danio rerio
140809 Homo sapiens
100858692 Gallus gallus
531606 Bos taurus
296271 Rattus norvegicus
76650 Mus musculus
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