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SVIL encodes a bipartite protein with distinct amino- and carboxy-terminal domains. Additionally we are shipping Supervillin Proteins (5) and Supervillin Kits (4) and many more products for this protein.
Showing 10 out of 40 products:
Human Polyclonal SVIL Primary Antibody for ICC, IF - ABIN4356969
Hiruma, Kamasaki, Otomo, Nemoto, Uehara: Dynamics and function of ERM proteins during cytokinesis in human cells. in FEBS letters 2017
This gene encodes a bipartite protein with distinct amino- and carboxy-terminal domains. The amino-terminus contains nuclear localization signals and the carboxy-terminus contains numerous consecutive sequences with extensive similarity to proteins in the gelsolin family of actin-binding proteins, which cap, nucleate, and/or sever actin filaments. The gene product is tightly associated with both actin filaments and plasma membranes, suggesting a role as a high-affinity link between the actin cytoskeleton and the membrane. The encoded protein appears to aid in both myosin II assembly during cell spreading and disassembly of focal adhesions. Two transcript variants encoding different isoforms of supervillin have been described.
, membrane-associated F-actin binding protein p205
, supervillin muscle-specific isoform