TATA Box Binding Protein (TBP) ELISA Kits

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. Additionally we are shipping TBP Antibodies (182) and TBP Proteins (34) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
TBP 6908 P20226
TBP 21374 P29037
TBP 117526  
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Top TBP ELISA Kits at antibodies-online.com

Showing 10 out of 31 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 11.72 pg/mL 46.88-3000 pg/mL Typical standard curve 96 Tests 13 to 16 Days
$1,026.67
Details
Mouse 0.188 ng/mL 0.313-20 ng/mL Typical standard curve 96 Tests 12 to 14 Days
$630.00
Details
Rat 0.094 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests 12 to 14 Days
$638.00
Details
Pig 0.938 ng/mL 1.563-100 ng/mL   96 Tests 12 to 14 Days
$715.00
Details
Chicken 0.938 ng/mL 1.563-100 ng/mL   96 Tests 12 to 14 Days
$715.00
Details
Rabbit 0.938 ng/mL 1.563-100 ng/mL   96 Tests 12 to 14 Days
$715.00
Details
Dog 1.0 ng/mL 5.0-100 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Monkey 0.938 ng/mL 1.563-100 ng/mL   96 Tests 12 to 14 Days
$715.00
Details
Guinea Pig
  96 Tests 15 to 18 Days
$707.14
Details
Sheep
  96 Tests 15 to 18 Days
$707.14
Details

More ELISA Kits for TBP Interaction Partners

Human TATA Box Binding Protein (TBP) interaction partners

  1. these findings provide a mechanistic model for the specific loading of TBP by TFIID onto the promoter.

  2. In an integrative approach combining crystal coordinates, biochemical analyses and data from cross-linking mass-spectrometry (CLMS), the authors determine the architecture of the TAF11/TAF13/TBP complex, revealing TAF11/TAF13 interaction with the DNA binding surface of TBP.

  3. these studies support the idea that increases in TBP expression contribute to enhanced VEGFA transcription early in colorectal cancer development to drive tumorigenesis.

  4. The genetic animal models of SCA17 clearly indicate that the phenotypes are dependent on the expression levels of mutant TBP and the length of CAG/glutamine repeat.

  5. we observed that carriers of either ATXN7 or TBP alleles with relatively large CAG repeat sizes in both alleles had a substantially increased risk of lifetime depression.

  6. Data indicate the crystal structure of a Brf2-TBP-Bdp1 complex bound to a DNA promoter.

  7. Study could not determine a definitive cutoff value for the pathologic CAG repeat number of SCA17.

  8. TBP attenuates Msx1-mediated glycoprotein hormone alpha transcriptional repression.

  9. this analysis of the 2.2-kb doubly spliced RNA (2.2DS-RNA) -mediated suppression of viral RNA expression showed that 2.2DS-RNA inhibited transcription via binding to the TATA-binding protein and stress granule proteins.

  10. Our results provide first evidence that Taspase1 processing affects TFIIA regulation of TFIID and suggest that Taspase1 processing of TFIIA is required to establish INR-selective core promoter activity in the presence of NC2.

  11. TBP (and GATA2 and Sp1) have key roles in inflammation and ischemia-like conditions through MAOA regulation.

  12. Deactivation of TBP contributes to SCA17 pathogenesis.

  13. HOXA2 acts as a suppressor or TBP-antagonist to inhibit MMP-9 expression; while methylation-mediated inactivation of HOXA2 in NPC derepresses MMP-9 production and increases invasion of NPC cells.

  14. The data reveal synergistic effects of H3K4me3, H3K14ac and a TATA box sequence on TFIID binding in vitro. Stoichiometry analyses of affinity purified human TFIID identified the presence of a stable dimeric core.

  15. The UL4 protein directly interacted with the host TBP and the carboxy-terminal domain of RNA polymerase II in infected cells.

  16. Findings indicate that using TATA-binding protein (TBP) alone or in combination with hydroxymethylbilane synthase (HMBS) as endogenous controls could be a reliable method for normalizing qRT-PCR data in hepatoma cell lines treated with TNF-alpha.

  17. Ethanol increases Pol III transcription through a response element which is composed of the overlapping Elk1 and AP-1 binding sites of the TBP promoter. The binding sites may play a role in ethanol-induced deregulation of Pol III genes in liver tumors.

  18. conclude that the oncoprotein HBXIP as a co-activator of TF II D transactivates Lin28B promoter via directly binding to TBP to upregulate the expression of Lin28B in promotion of proliferation of breast cancer cells

  19. This study showed that five families with SCA17 represents a significant portion of ataxia cases in the population of the Czech Republic.

  20. This study created a first transgenic rat model for SCA17 that carries a full human cDNA fragment of the TBP gene with 64 CAA/CAG repeats (TBPQ64).

Mouse (Murine) TATA Box Binding Protein (TBP) interaction partners

  1. TBP promotes the association of RNA Polymerase II with mitotic chromosomes, and facilitates transcriptional reactivation following mitosis.

  2. the TAF10-containing canonical TFIID and SAGA complexes are dispensable for early paraxial mesoderm development, arguing against the generic role in transcription proposed for these fully assembled holo-complexes

  3. Our study establishes glial dysfunction as an important component of SCA17 pathogenesis and suggests targeting glial inflammation as a potential therapeutic approach for SCA17 treatment.

  4. This evidence demonstrates that TBP2 does not replace TBP during muscle differentiation, as previously proposed, with limiting amounts of TFIID-TBP being required to promote muscle-specific gene expression

  5. The large TBP polyQ repeat decreases the association of MyoD with TBP and DNA promoters and causes muscle degeneration in spinocerebellar ataxia 17 transgenic mice.

  6. Thus, modulating the levels of both Huwe1 and USP10 appears to fine-tune the requisite degradation of TBP during myogenesis.

  7. This study demonistrated that denervation-induced muscle atrophy on Tbp expression in mice.

  8. The results of this study confirmed motor deficits in the Tbp/Q71 mice and present previously unrecognized behavioral characteristics obtained from the automated home cage, indicating its use for high-throughput screening and testing.

  9. TBP might be a marker for transmitting cellular memory to daughter cells.

  10. we show that the differentiation of fetal liver progenitors to adult hepatocytes involves a wholesale depletion of canonical cofactor required for Sp1 activation/Mediator and TFIID complexes at both the RNA and protein level

  11. Alcohol induces RNA polymerase III-dependent transcription through c-Jun by co-regulating TATA-binding protein (TBP) and Brf1 expression.

  12. Data show that down-regulation of TrkA also occurs in the cerebellum of SCA17 transgenic mice prior to Purkinje cell degeneration.

  13. Developmental specificity of recruitment of TBP to the TATA box of the human gamma-globin gene

  14. TBP N terminus functions in transcriptional regulation of a placental beta2m-dependent process that favors maternal immunotolerance of pregnancy.

  15. results show a differential dependency of the RNA polymerases on TBP and provide evidence for TBP-independent pol II transcriptional mechanisms that allow reinitiation and maintenance of gene transcription in vivo

  16. Fundamental cellular processes do not require vertebrate-specific sequences within this protein.

  17. TFIID stability requires TAF10 protein in mouse embryonic cells

  18. required for the regulation of spermatogonial stem cell specification and proliferation

  19. analysis of gene regulatory interplay between TBP, PIAS1, PIAS3, PIASx, PIASy, ZFP523, and transcription factors

  20. JNK1 and JNK2 differentially regulate TBP through Elk-1, controlling c-Jun expression and cell proliferation

Zebrafish TATA Box Binding Protein (TBP) interaction partners

  1. TBP plays an important role in the degradation of a specific subset of maternal mRNAs during late blastulation/early gastrulation, which involves targets of the miR-430 pathway.

Fruit Fly (Drosophila melanogaster) TATA Box Binding Protein (TBP) interaction partners

  1. Results indicate that a portion of Brf1 is sandwiched between Bdp1 and TBP upstream of the U6 TATA box. Furthermore, Bdp1 traverses the DNA under the N-terminal stirrup of TBP to interact with the DNA (and very likely Brf1) downstream of the TATA sequence.

  2. TFIID has two disctinct modes of transcription initiation, de novo initiation and reinitiation, as revealed by the inhibitory effect of TFIID-bound tin compounds on the de novo initiation, but not on the reinitiation.

  3. Deactivation of TBP contributes to SCA17 pathogenesis.

  4. Aptamers generated by both selections were able to bind specifically to TBP, but the two groups showed characteristics which were clearly different in terms of their capability to compete with TATA-DNA.

  5. in fruit flies, different classes of RNA polymerase III promoters differentially utilize TBP and TRF1 for the initiation of transcription.

  6. Tbp targets core histone transcription.

  7. TBP activates TATA-dependent transcription and represses DPE-dependent transcription, whereas Mot1 and NC2 block TBP function and thus repress TATA-dependent transcription and activate DPE-dependent transcription.

TBP Antigen Profile

Antigen Summary

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TBP

  • TATA-box binding protein (TBP) antibody
  • TATA box binding protein (Tbp) antibody
  • TATA box binding protein (tbp) antibody
  • TATA box binding protein (TBP) antibody
  • TATA-box binding protein (tbp) antibody
  • TATA binding protein (Tbp) antibody
  • TATA-box binding protein L homeolog (tbp.L) antibody
  • TATA-box binding protein (Tbp) antibody
  • TATA-box-binding protein (Tbp) antibody
  • TATA-box binding protein S homeolog (tbp.S) antibody
  • CG9874 antibody
  • Dmel\\CG9874 antibody
  • dtbp antibody
  • dTFIID antibody
  • fd20h06 antibody
  • gtf2d antibody
  • gtf2d1 antibody
  • HDL4 antibody
  • RBP antibody
  • sca17 antibody
  • si:zc101n13.2 antibody
  • tbp antibody
  • tbp-a antibody
  • tbp-b antibody
  • TBP1 antibody
  • TBP38 antibody
  • tfiid antibody
  • tfiidtau antibody
  • wu:fd20h06 antibody
  • xtbp antibody
  • zgc:66213 antibody

Protein level used designations for TBP

TATA sequence-binding protein , TATA-box binding protein N-terminal domain , TATA-box factor , TATA-box-binding protein , transcription initiation factor TFIID TBP subunit , TATA-binding factor , TATA-binding protein , TFIID core protein , zTBP , zfTBF , TA-TA binding protein 1 , TATA binding protein , TATA box binding protein , 42kDa polypeptide , CG9874-PA , TATA box-binding protein , TATA-box binding protein , Tbp-PA , transcription factor , Transcription initiation factor TFIID TBP subunit , TATA-box binding protein S homeolog

GENE ID SPECIES
6908 Homo sapiens
21374 Mus musculus
117526 Rattus norvegicus
368882 Danio rerio
395995 Gallus gallus
516578 Bos taurus
611193 Canis lupus familiaris
696258 Macaca mulatta
738472 Pan troglodytes
780434 Sus scrofa
100101451 Takifugu rubripes
100144760 Ovis aries
100380389 Salmo salar
37476 Drosophila melanogaster
399465 Xenopus laevis
101839769 Mesocricetus auratus
692612 Bombyx mori
100733307 Cavia porcellus
503680 Xenopus laevis
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