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Tumor necrosis factor (TNF\; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). Additionally we are shipping TRAF7 Proteins (3) and and many more products for this protein.
Showing 10 out of 32 products:
Horse (Equine) Polyclonal TRAF7 Primary Antibody for IP, WB - ABIN269571
Zotti, Uva, Ferravante, Vessichelli, Scudiero, Ceccarelli, Vito, Stilo: TRAF7 protein promotes Lys-29-linked polyubiquitination of IkappaB kinase (IKKgamma)/NF-kappaB essential modulator (NEMO) and p65/RelA protein and represses NF-kappaB activation. in The Journal of biological chemistry 2011
TRAF7 is involved in signal transduction pathways that lead either to activation or repression of NF-kappaB (show NFKB1 Antibodies) transcription factor.
These results suggest a new mechanism by which MyoD1 (show MYOD1 Antibodies) function is coupled to NF-kappaB (show NFKB1 Antibodies) activity through Traf7, regulating the balance between cell cycle progression and differentiation during myogenesis.
TRAF7 negatively regulates c-Myb (show MYB Antibodies) activity by sequestering c-Myb (show MYB Antibodies) to the cytosol via sumoylation.
TRAF7 mutations icause intraneural perineuriomas.
TRAF7 is a direct target of miR (show MLXIP Antibodies)-126 in human umbilical cord vascular endothelial cells.
Downregulation of ubiquitin E3 ligase TNF receptor-associated factor 7 leads to stabilization of p53 (show TP53 Antibodies) in breast cancer.
The findings of this study suggested an essential contribution of combined KLF4 (show KLF4 Antibodies) K409Q and TRAF7 mutations in the genesis of secretory meningioma and demonstrate a role for TRAF7 alterations in other non-NF2 (show NF2 Antibodies) meningiomas.
Nearly one-fourth of all meningiomas have mutations in TRAF7.
an important role for TRAF7 in the activation of JNK (show MAPK8 Antibodies) following TNFalpha (show TNF Antibodies) stimulation and involvement of this protein in regulating the turnover of c-FLIP (show CFLAR Antibodies)
this study identifies TRAF7 as a NEMO (show IKBKG Antibodies)- and p65 (show GORASP1 Antibodies)-interacting molecule and brings important information on the ubiquitination events that control NF-kappaB (show NFKB1 Antibodies) transcriptional activity.
TRAF7 potentiates MEKK3 (show MAP3K3 Antibodies)-induced AP1 (show FOSB Antibodies) and CHOP (show DDIT3 Antibodies) activation and induces apoptosis
Tumor necrosis factor (TNF\; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs\; a coiled-coil (leucine zipper) motif\; and a homologous region that defines the TRAF family, the TRAF domain, which is involved in self-association and receptor binding.
TNF receptor-associated factor 7
, ring finger and WD repeat domain 1
, E3 ubiquitin-protein ligase TRAF7
, e3 ubiquitin-protein ligase TRAF7-like
, RING finger and WD repeat-containing protein 1
, RING finger protein 119