anti-TRAFs and NIK-Associated Protein Antibodies

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific).

Data Quality
  • 3
Type
  • 4
    Primary antibodies
Antigen
  • 4
Reactivity
  • 4
  • 4
  • 2
Application
  • 4
  • 3
  • 2
  • 1
  • 1
Host
  • 4
Clonality
  • 3
  • 1
Binding Specificity
  • 2
  • 1
Isotype
  • 3
Format
  • 3
4 Products
ReactivityHuman, Rat (Rattus)
Application ELISA, IHC (p), WB
Order details Cat. No. ABIN3181417
$359.79
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application ELISA, WB
Order details Cat. No. ABIN3187293
$359.79
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application FACS, ICC, IHC, IP, WB
Order details Cat. No. ABIN6719077
$398.00
100 μL
Plus shipping costs $45.00
Delivery in 6 to 11 Business Days
ReactivityHuman, Rat (Rattus)
Application ELISA, IHC (p), WB
Order details Cat. No. ABIN5955603
$438.90
Plus shipping costs $45.00
Delivery in 12 to 14 Business Days
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TRAFs and NIK-Associated Protein (TNAP) Antigen Profile

Protein Summary

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization\; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with TNAP

  • alkaline phosphatase, liver/bone/kidney (ALPL) antibody
  • alkaline phosphatase, liver/bone/kidney (Alpl) antibody
  • Akp-2 antibody
  • Akp2 antibody
  • AP-TNAP antibody
  • APTNAP antibody
  • HOPS antibody
  • TNAP antibody
  • TNSALP antibody

Protein level used designations for TNAP

alkaline phosphatase liver/bone/kidney isozyme , alkaline phosphatase, tissue-nonspecific isozyme , alkaline phosphomonoesterase , glycerophosphatase , liver/bone/kidney-type alkaline phosphatase , tissue-nonspecific ALP , alkaline phosphatase 2, liver

GENE ID SPECIES
249 Homo sapiens
11647 Mus musculus
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