Tachykinin, Precursor 1 Proteins (TAC1)

TAC1 encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. Additionally we are shipping Tachykinin, Precursor 1 Antibodies (217) and Tachykinin, Precursor 1 Kits (137) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TAC1 6863 P20366
Rat TAC1 TAC1 24806 P06767
Mouse TAC1 TAC1 21333 P41539
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Top Tachykinin, Precursor 1 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag   50 μg Log in to see 4 Days
$522.50
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Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$225.40
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Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$400.00
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Escherichia coli (E. coli) Human His tag   10 μg Log in to see 15 to 16 Days
$300.00
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Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 18 Days
$582.75
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Synthetic Human Un-conjugated   100 μg Log in to see 11 to 18 Days
$540.11
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Synthetic Human Un-conjugated   100 μg Log in to see 15 to 18 Days
$560.00
Details

TAC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for Tachykinin, Precursor 1 (TAC1) Interaction Partners

Human Tachykinin, Precursor 1 (TAC1) interaction partners

  1. Preincubation of LAD2 cells with the natural flavonoid methoxyluteolin (1-100 mM) inhibits (P < 0.0001) secretion and gene expression of IL-1beta (show IL1B Proteins), procaspase-1, and pro-IL-1beta (show IL1B Proteins). Mast cell secretion of IL-1beta (show IL1B Proteins) in response to SP and IL-33 (show IL33 Proteins) reveals targets for the development of antiinflammatory therapies.

  2. High TAC1 expression is associated with primary central nervous system lymphoma.

  3. These findings reported here for the first time suggest an important role for a SP/NK1R (show TACR1 Proteins) system, either as genetic and/or epigenetic factor, in both the cytoplasm and nucleus functions of the adipose stem cells.

  4. This study showed that ADMA, carbonyl groups, CAT and NKA can be useful markers of chronic stress in both males and females with depression, PTSD, and depression concurrent with PTSD.

  5. Inhibition of SP through use of a neurokinin 1 (NK1) antagonist is highly beneficial following both traumatic brain injury (TBI) and ischaemic stroke in pre-clinical models. The role of CGRP (show S100A12 Proteins) is more unclear, especially with respect to TBI, with both elevations and reductions in CGRP (show S100A12 Proteins) levels reported following trauma

  6. elevated plasma SP level, up-regulated expression of SP and NK1R (show TACR1 Proteins) indicate that the SP/NK1R (show TACR1 Proteins) complex is important in the development of Atopic dermatitis.

  7. High methylation of TAC1 is associated with head and neck cancer.

  8. Data suggest that serum substance P concentrations at the day of oocyte retrieval after ovulation induction may be used to predict oocyte maturation during in vitro oocyte maturation to be followed by intracytoplasmic sperm injections and may be an indirect indicator for treatment outcome in women with infertility.

  9. Expression substance P/neurokinin A/hemokinin-1 and their preferred neurokinin 1/neurokinin 2 receptors are dysregulated in uterine leiomyomata.

  10. These results suggest that Substance P can retain the therapeutic effect of adipose-derived stem cells by elevating their proliferative and paracrine potential in ex vivo culture.

Mouse (Murine) Tachykinin, Precursor 1 (TAC1) interaction partners

  1. these results show that substance P regulates the production of LTB4 (show PTGR1 Proteins) via PKCalpha (show PKCa Proteins)/MAPK (show MAPK1 Proteins) pathway, which further promotes AP-associated ALI through neutrophil reverse transendothelial cell migration

  2. This study demonstrated that BoNT/A antinociceptive activity is dependent on integrity of SP/NKA and NK1R (show TACR1 Proteins).

  3. elevated plasma SP level, up-regulated expression of SP and NK1R (show TACR1 Proteins) indicate that the SP/NK1R (show TACR1 Proteins) complex is important in the development of Atopic dermatitis.

  4. Evidence for a role of Tac1 in the control of reproductive function in the male mouse, suggesting a predominant central action that may involve a change in the balance of neural factors that control GnRH expression.

  5. This study demonstrated that Activity of Tachykinin1-Expressing Pet1 (show FEV Proteins) Raphe Neurons Modulates the Respiratory Chemoreflex.

  6. RNA-binding protein Msi1 (show MSI1 Proteins) competes with miR130a and -206 for interaction with TAC1 mRNA, to stabilize and increase its translation

  7. Results reveal that EM-2, Leu-Enk (show PENK Proteins) and Dyn (show PDYN Proteins) A were down-regulated in Tac1-/- spinal cord tissues.

  8. Results provide evidence linking enhanced waking activity and the pro-inflammatory molecule substance P to changes in slow-wave activity associated with sleep-active cortical cells that co-express nNOS (show NOS1 Proteins) and the NK-1R (show TACR1 Proteins)

  9. Substance P partly accounts for the increased density of microglia in the substantia nigra through chemotaxic recruitment via a novel NK1R (show TACR1 Proteins)-NOX2 (show CYBB Proteins) axis-mediated pathway.

  10. We conclude that a dedicated subset of VMHVL neurons marked by ERalpha (show ESR1 Proteins), NKX2-1 (show NKX2-1 Proteins), and Tac1 regulates estrogen-dependent fluctuations in physical activity and constitutes one of several neuroendocrine modules that drive sex-specific responses.

Cow (Bovine) Tachykinin, Precursor 1 (TAC1) interaction partners

  1. Substance P alters the cytokine and chemokine (show CCL1 Proteins) expression pattern in monocytes and blood-monocyte-derived macrophages.

Rabbit Tachykinin, Precursor 1 (TAC1) interaction partners

  1. There is an increase in the sensitivity of rapidly adapting receptor (RAR (show RAB40B Proteins)) activity to substance P (SP) during high altitude exposure.

  2. Increased substance P-production precedes tendinosis, since tendinosis-like changes occur only after a minimum of 3 weeks of exercise

Tachykinin, Precursor 1 (TAC1) Protein Profile

Protein Summary

This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Tachykinin, Precursor 1 Proteins (TAC1)

  • tachykinin precursor 1 (TAC1)
  • tachykinin, precursor 1 (Tac1)
  • tachykinin 1 (Tac1)
  • tachykinin precursor 1 (tac1)
  • tachykinin precursor 1 L homeolog (tac1.L)
  • 4930528L02Rik protein
  • beta-PPT-A protein
  • Hs.2563 protein
  • NK-1 protein
  • NK1 protein
  • nk2 protein
  • NKA protein
  • nkna protein
  • npk protein
  • PPT protein
  • PPT-A protein
  • Ppt5fl protein
  • PPTA protein
  • PPTA3 protein
  • RATPPTA3 protein
  • SP protein
  • TAC protein
  • tac1 protein
  • tac2 protein
  • tachykinin protein

Protein level used designations for Tachykinin, Precursor 1 Proteins (TAC1)

PPT , neurokinin 1 , neurokinin 2 , neurokinin A , neurokinin alpha , neuromedin L , neuropeptide K , neuropeptide gamma , preprotachykinin , protachykinin-1 , substance K , substance P , tachykinin 2 , tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma) , Tachykinin (substance P, neurokinin A, neuropeptide K, neuropeptide gamma) , tachykinin 1 , tachykinin, precursor 1 , delta preprotachykinin I , preprotachykinin A , protachykinin-1 preproprotein , preprotachykinin I , substance P, neuropeptide gamma, neurokinin A , Substance P , tachykinin precursor 1 L homeolog

GENE ID SPECIES
6863 Homo sapiens
24806 Rattus norvegicus
475239 Canis lupus familiaris
697350 Macaca mulatta
100034669 Ovis aries
100379583 Cavia porcellus
100528498 Ictalurus punctatus
21333 Mus musculus
281512 Bos taurus
420573 Gallus gallus
100009275 Oryctolagus cuniculus
100052324 Equus caballus
735077 Xenopus laevis
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