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Structural component of ciliary and flagellar microtubules. Additionally we are shipping Tektin 4 Proteins (6) and and many more products for this protein.
Showing 10 out of 48 products:
Overexpressed miR (show MLXIP Antibodies)-150 attenuates hypoxia-induced human cardiomyocyte cell apoptosis by targeting GRP94 (show HSP90B1 Antibodies).
Regulation of CLC-1 (show CLCN1 Antibodies) chloride channel (show CLCA1 Antibodies) biosynthesis by FKBP8 (show FKBP8 Antibodies) and Hsp90beta (show HSP90AB1 Antibodies) as a molecular model for myotonia congenita has been described.
Study demonstrated that the lack of gp96 (show HSP90B1 Antibodies) in both the human monocytic cell line MM6 and in macrophages from LysMcre-gp96 (show HSP90B1 Antibodies) floxed mice neither leads to a complete loss of TLR 2 expression nor to a complete loss of TLR-induced signaling, but is associated with an impaired phosphorylation of ERK (show EPHB2 Antibodies) and p38 (show CRK Antibodies). These results reveal for the first time a crucial role for gp96 (show HSP90B1 Antibodies) in the regulation of ERK (show EPHB2 Antibodies) and p38 (show CRK Antibodies) kinases.
HSP-gp96 (show HSP90B1 Antibodies) promotes T cell response, enhances DC antigen presentation and induces cytokine secretion in human gastric cancer cell lines.
our results besides adding further evidence in support of Grp94 (show HSP90B1 Antibodies) as the shared tumor antigen in tumors of the GI tract, prove that it can be measured in plasma as valuable diagnostic marker of disease in the form of complexes with IgG that also exert immune-modulating activities on circulating immune cells.
High GRP94 (show HSP90B1 Antibodies) expression is associated with endometrioid adenocarcinoma.
Immuno-stimulating peptide derived from HMGB1 (show HMGB1 Antibodies) is more effective than the N-terminal domain of Gp96 (show HSP90B1 Antibodies) as an endogenous adjuvant for improvement of protein vaccines.
These data demonstrate the essential role of the gp96 (show HSP90B1 Antibodies)-TLR interaction in priming T cell immunity and provide further molecular basis for the coupling of gp96 (show HSP90B1 Antibodies)-mediated innate with adaptive immunity.
mutations in GRP94 (show HSP90B1 Antibodies) that affect its IGF chaperone activity represent a novel causal genetic mechanism that limits IGF biosynthesis, quite a distinct mechanism from the known genes in the GH/IGF signaling network.
In this instance, the ATP5B (show ATP5B Antibodies)/CALR (show CALR Antibodies)/HSP90B1 (show HSP90B1 Antibodies)/HSPB1 (show HSPB1 Antibodies)/HSPD1 (show HSPD1 Antibodies)-signaling network was revealed as the predominant target which was associated with the majority of the observed protein-protein interactions. As a result, the identified targets may be useful in explaining the anticancer mechanisms of ursolic acid and as potential targets for colorectal cancer therapy.
Data suggest that Tektin 4 is not associated with axonemal tubulins but instead associated with Outer Dense Fibers (show ODF1 Antibodies) in rodent spermatozoa.
TEKT4 is necessary for the proper coordinated beating of the sperm flagellum and male reproductive physiology
This study demonstrates that the expression patterns of tektin-4 were a proxy for an effect on spermatozoa motility and consequently bull infertility.
This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15.
94 kDa glucose-regulated protein
, endothelial cell (HBMEC) glycoprotein
, heat shock protein 90 kDa beta member 1
, stress-inducible tumor rejection antigen gp96
, tumor rejection antigen (gp96) 1
, tumor rejection antigen 1
, testicular microtubules-related protein 4
, tektin 4