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The protein encoded by TSPAN6 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Additionally we are shipping Tetraspanin 6 Proteins (4) and and many more products for this protein.
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Human Polyclonal Tetraspanin 6 Primary Antibody for FACS, WB - ABIN6242668
Salas, Callaerts-Vegh, Arranz, Guix, DHooge, Esteban, De Strooper, Dotti: Tetraspanin 6: A novel regulator of hippocampal synaptic transmission and long term plasticity. in PLoS ONE 2017
Show all 2 Pubmed References
Results shows that TSPAN6 is a crucial player in Amyloid Precursor Protein-C-terminal fragment turnover
TSPAN6 functions as a negative regulator of the RLR pathway by interacting with MAVS in a ubiquitination-dependent manner.
Tspan6 KO mice show normal locomotor behaviour and no defects in hippocampus-dependent memory tests.
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2. The use of alternate polyadenylation sites has been found for this gene.
, tetraspanin 6
, tetraspanin F139
, transmembrane 4 superfamily member 6
, A15 homolog
, putative NF-kappa-B-activating protein 321
, tetraspan TM4SF
, tetraspanin TM4-D