Protein Summary

This gene encodes a member of the PAR (proline and acidic amino acid-rich) subfamily of basic region/leucine zipper (bZIP) transcription factors. It is expressed in a broad range of cells and tissues in adult animals, however, during embryonic development, TEF expression appears to be restricted to the developing anterior pituitary gland, coincident with the appearance of thyroid-stimulating hormone, beta (TSHB). Indeed, TEF can bind to, and transactivate the TSHB promoter. It shows homology (in the functional domains) with other members of the PAR-bZIP subfamily of transcription factors, which include albumin D box-binding protein (DBP), human hepatic leukemia factor (HLF) and chicken vitellogenin gene-binding protein (VBP)\; VBP is considered the chicken homologue of TEF. Different members of the subfamily can readily form heterodimers, and share DNA-binding, and transcriptional regulatory properties. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TEF

• thyrotrophic embryonic factor a (tefa) antibody
• thyrotrophic embryonic factor (tef) antibody
• TEF, PAR bZIP transcription factor (TEF) antibody
• thyrotroph embryonic factor (Tef) antibody
• TEF, PAR bZIP transcription factor (Tef) antibody

• 2310028D20Rik antibody
• DKFZp459A027 antibody
• TEF antibody
• tefb antibody
• tefbeta antibody
• Show all synonym aliases
• VBP antibody
• wu:fa12f02 antibody
• wu:fb11h02 antibody
• xtef antibody
• zTEF[a] antibody

Protein level used designations for TEF

thyrotroph embryonic factor beta , thyrotrophic embryonic factor , thyrotroph embryonic factor , thyrotroph embryonic factor homolog , transcription factor VBP , vitellogenin binding protein (VBP), beta/beta isoform , vitellogenin gene-binding protein