Thyrotrophic Embryonic Factor Proteins (TEF)

TEF encodes a member of the PAR (proline and acidic amino acid-rich) subfamily of basic region/leucine zipper (bZIP) transcription factors. Additionally we are shipping TEF Antibodies (45) and TEF Kits (28) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TEF 21685 Q9JLC6
TEF 7008 Q10587
TEF 29362 P41224
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Top TEF Proteins at antibodies-online.com

Showing 7 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
Details
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 13 to 16 Days
$953.85
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Yeast Phodopus sungorus His tag   1 mg Log in to see 60 to 71 Days
$2,552.00
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,799.50
Details
Yeast Chicken His tag   1 mg Log in to see 60 to 71 Days
$2,856.33
Details

TEF Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,
Rat (Rattus)

More Proteins for Thyrotrophic Embryonic Factor (TEF) Interaction Partners

Zebrafish Thyrotrophic Embryonic Factor (TEF) interaction partners

  1. TEF regulates light-induced transcription of DNA repair genes.

Mouse (Murine) Thyrotrophic Embryonic Factor (TEF) interaction partners

  1. Upregulation of TEF expression significantly retarded Bladder Cancer cell growth by inhibiting the G1/S transition via regulating AKT/FOXOs signalling.

  2. In Ccdc80(-/-) mice, expression of the core clock member Arntl/Bmal1 was reduced whereas that of the oscillating transcription factors Dbp and Tef was increased in all tissues examined.

  3. evidence of TEF regulation through a miR-125b-mediated pathway

  4. Data show that S100a9, Mmp10 and Ang2 were among the most downregulated genes, whereas Per3, Tef and Prdx6 were significantly upregulated in the DMH + Calcium group.

  5. we demonstrate that D site albumin promoter binding protein/thyrotroph embryonic factor/hepatic leukemia factor triple knockout mice develop cardiac hypertrophy and left ventricular dysfunction associated with a low blood pressure

  6. TEF contributes to the activation of the telokin promoter in smooth muscle cells in a calcium-dependent manner

  7. mice deficient for all three PAR bZip proteins (DBP,HLF,& TEF) are highly susceptible to generalized spontaneous and audiogenic epilepsies, frequently lethal. Pyridoxal kinase is a target gene of PAR bZip proteins in both liver and brain

  8. The Tef protein control the expression of many enzymes and regulators involved in detoxification and drug metabolism, such as cytochrome P450 enzymes, carboxylesterases, and constitutive androstane receptor (CAR).

  9. Data show that the clock knockout mice or mice devoid of dbp/hlf/tef (triple knockout) exhibit significant changes in renal expression of several key regulators of water or sodium balance.

Human Thyrotrophic Embryonic Factor (TEF) interaction partners

  1. TEF is downregulated in bladder cancer and correlates with poor patient survival.

  2. Resequencing three candidate genes (HOMER1, SLC6A4, and TEF) discovers seven potentially deleterious variants susceptibility to major depressive disorder and suicide attempts in Chinese.

  3. findings show the polymorphisms of Cry1 rs2287161 and Tef rs738499 are associated to major depressive disorder in the Chinese population

  4. The polymorphism of Tef rs738499 is associated with depression symptoms in parkinson disease.

  5. the TT genotype in Tef rs738499 is associated with sleep disturbances in Parkinson disease.

  6. evidence of TEF regulation through a miR-125b-mediated pathway

  7. TEF-expressing cells accumulated in G(0)/G(1) phase without undergoing apoptosis.

TEF Protein Profile

Protein Summary

This gene encodes a member of the PAR (proline and acidic amino acid-rich) subfamily of basic region/leucine zipper (bZIP) transcription factors. It is expressed in a broad range of cells and tissues in adult animals, however, during embryonic development, TEF expression appears to be restricted to the developing anterior pituitary gland, coincident with the appearance of thyroid-stimulating hormone, beta (TSHB). Indeed, TEF can bind to, and transactivate the TSHB promoter. It shows homology (in the functional domains) with other members of the PAR-bZIP subfamily of transcription factors, which include albumin D box-binding protein (DBP), human hepatic leukemia factor (HLF) and chicken vitellogenin gene-binding protein (VBP)\; VBP is considered the chicken homologue of TEF. Different members of the subfamily can readily form heterodimers, and share DNA-binding, and transcriptional regulatory properties. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TEF

  • thyrotrophic embryonic factor a (tefa)
  • thyrotrophic embryonic factor (tef)
  • TEF, PAR bZIP transcription factor (TEF)
  • thyrotroph embryonic factor (Tef)
  • TEF, PAR bZIP transcription factor (Tef)
  • 2310028D20Rik protein
  • DKFZp459A027 protein
  • TEF protein
  • tefb protein
  • tefbeta protein
  • VBP protein
  • wu:fa12f02 protein
  • wu:fb11h02 protein
  • xtef protein
  • zTEF[a] protein

Protein level used designations for TEF

thyrotroph embryonic factor beta , thyrotrophic embryonic factor , thyrotroph embryonic factor , thyrotroph embryonic factor homolog , transcription factor VBP , vitellogenin binding protein (VBP), beta/beta isoform , vitellogenin gene-binding protein

GENE ID SPECIES
30674 Danio rerio
550073 Xenopus (Silurana) tropicalis
100173555 Pongo abelii
21685 Mus musculus
7008 Homo sapiens
607883 Canis lupus familiaris
29362 Rattus norvegicus
396342 Gallus gallus
616076 Bos taurus
100192430 Ovis aries
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