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Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Additionally we are shipping Transcription Factor EB Antibodies (155) and and many more products for this protein.
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Human TFEB Protein expressed in Escherichia coli (E. coli) - ABIN2733467
Song, Sun, Peluso, Zeng, Yu, Lu, Xu, Wang, Liu, Huang, Chen, Durairajan, Zhang, Zhou, Zhang, Lu, Ballabio, Medina, Guo, Li: A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition. in Autophagy 2016
Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T- cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta.
transcription factor EB
, transcription factor EB-like
, T-cell transcription factor EB
, class E basic helix-loop-helix protein 35