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TRIM69 encodes a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif, a PRY domain and a C-terminal SPRY domain. Additionally we are shipping Tripartite Motif Containing 69 Antibodies (89) and and many more products for this protein.
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TRIM69 restricts dengue virus replication by specifically ubiquitinating viral nonstructural protein NS3.
hTRIM69 is a novel E3 ubiquitin ligase identified from human testis and may function to ubiquitinate its particular substrates during spermatogenesis.
Gene and protein analysis of the mouse counterpart.
This gene encodes a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif, a PRY domain and a C-terminal SPRY domain. The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and, when overexpressed, induces apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.
tripartite motif-containing 69
, tripartite motif containing 69
, tripartite motif-containing protein 69-like
, E3 ubiquitin-protein ligase TRIM69
, RFP-like domain-containing protein trimless
, ring finger protein 36
, tripartite motif protein 69
, tripartite motif-containing protein 69
, RFP-like (B30.2) domain protein
, RING finger B-box coiled-coil transcription factor
, testis-specific RING finger protein