Tripartite Motif Containing 72 Proteins
Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites.
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Tripartite Motif Containing 72 (TRIM72) (AA 1-477) protein (His tag) Protein
Tripartite Motif Containing 72 (TRIM72) (AA 1-477) protein (His tag) Protein
Tripartite Motif Containing 72 (TRIM72) (AA 1-269) protein (GST tag) Protein
Tripartite Motif Containing 72 (TRIM72) (AA 378-477) protein (GST tag) Protein
Tripartite Motif Containing 72 (TRIM72) protein (Myc-DYKDDDDK Tag) Protein
Tripartite Motif Containing 72 (TRIM72) (AA 1-477) protein (His tag) Protein
Tripartite Motif Containing 72 (TRIM72) (AA 1-477) protein (His tag) Protein
Tripartite Motif Containing 72 (TRIM72) (AA 1-477) protein (His tag) Protein
Tripartite Motif Containing 72 (TRIM72) (AA 1-477) protein (His tag) Protein
Tripartite Motif Containing 72 (TRIM72) Protein Profile
Protein Summary
Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles (By similarity).
Gene names and symbols associated with TRIM72
- tripartite motif containing 72 (TRIM72) antibody
- tripartite motif containing 72, E3 ubiquitin protein ligase L homeolog (trim72.L) antibody
- tripartite motif-containing 72 (Trim72) antibody
- tripartite motif containing 72 (Trim72) antibody
- BC067209 antibody
- Mg53 antibody
- RGD1562778 antibody
- Trim72 antibody
Protein level used designations for TRIM72
tripartite motif-containing 72 , mitsugumin-53 , tripartite motif-containing protein 72 , Mitsugumin-53 , mitsugumin 53 , mg53
GENE ID | SPECIES |
---|---|
467960 | Pan troglodytes |
100008639 | Oryctolagus cuniculus |
493829 | Homo sapiens |
489927 | Canis lupus familiaris |
528804 | Bos taurus |
379612 | Xenopus laevis |
434246 | Mus musculus |
365377 | Rattus norvegicus |