Twisted Gastrulation Homolog 1 (Drosophila) (TWSG1) ELISA Kits

May be involved in dorsoventral axis formation.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse TWSG1 TWSG1 65960 Q9EP52
Anti-Human TWSG1 TWSG1 57045 Q9GZX9
Anti-Rat TWSG1 TWSG1 363294  
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Showing 2 out of 7 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.122 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Log in to see 13 to 16 Days
Mouse 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days

More ELISA Kits for TWSG1 Interaction Partners

Zebrafish Twisted Gastrulation Homolog 1 (Drosophila) (TWSG1) interaction partners

  1. Twisted gastrulation enhances BMP signaling through chordin (show CHRD ELISA Kits) dependent and independent mechanisms

Mouse (Murine) Twisted Gastrulation Homolog 1 (Drosophila) (TWSG1) interaction partners

  1. Our results show that BMP binding is required for TWSG1-mediated inhibition of osteoclast formation and function, and validate the critical functional regions within the TWSG1 protein for these interactions

  2. The goal of this study was to examine whether mice carrying a mutation in a gene encoding Twsg1, which is associated with a low penetrance of holoprosencephaly, are sensitized to retinoic acid teratogenesis.

  3. BMP-binding protein twisted gastrulation is required in mammary gland epithelium for normal ductal elongation and myoepithelial compartmentalization.

  4. Data show that Bmp4 (show BMP4 ELISA Kits), Bmp7 (show BMP7 ELISA Kits), Gremlin (show GREM1 ELISA Kits) and Twisted gastrulation (Twsg1) are all expressed in the thymus and expression was clearly different for each gene investigated.

  5. suggesting that Twsg1 expression in B cells serves to interpret BMP signals on a per-cell basis

  6. These results demonstrate that phenotypic variability in Twsg1-/- mice is associated with differential expression of certain developmentally regulated genes, and that craniofacial defects can be partially rescued by reduced p53 (show TP53 ELISA Kits) levels.

  7. TWSG1 overexpression inhibits RANKL (show TNFSF11 ELISA Kits)-induced osteoclast differentiation

  8. TWSG1 appears to be the main regulator of BMP present in CP.

  9. Cv2 (show BMPER ELISA Kits) enhances pro-BMP activity of Tsg.

  10. The developmentally regulated expression of Twisted gastrulation reveals a role for bone morphogenetic proteins in the control of T cell development.

Human Twisted Gastrulation Homolog 1 (Drosophila) (TWSG1) interaction partners

  1. Findings indicate that twisted gastrulation homolog 1 (TWSG1) maybe serves as a tumor suppressor gene in gastric cancer and potential biomarker or therapeutic target for the diagnosis and treatment of gastric cancer.

  2. Tsg functions as a BMP-agonist by inducing conformational change in chordin (show CHRD ELISA Kits) making it more susceptible to tolloid (show BMP1 ELISA Kits) cleavage and as a BMP-antagonist either independently or via a chordin (show CHRD ELISA Kits)-mediated mechanism.

  3. Data suggest CHRD (chordin) cleavage by tolloid-like metalloproteinases is insufficient to regulate BMP(bone morphogenetic protein)/BMPR signaling; CHRD fragments and TSG (twisted gastrulation protein) contribute to inhibition of BMP/BMPR signaling.

  4. these results suggest that BMPER and Tsg maintain a fine-tuned equilibrium that controls BMP pathway activity and is necessary for vascular cell homeostasis.

  5. mutations in the twisted gastrulation homolog 1 gene are neither a common direct cause nor a frequent modifying factor for human holoprosencephaly pathologies

  6. Tsg functions as an agonist synergizing with TGF-beta (show TGFB1 ELISA Kits) to inhibit T-cell activation.

  7. interferes with BMP-mediated hepcidin (show HAMP ELISA Kits) expression and may act with GDF15 (show GDF15 ELISA Kits) to dysregulate iron homeostasis in thalassemia syndromes.

Cow (Bovine) Twisted Gastrulation Homolog 1 (Drosophila) (TWSG1) interaction partners

  1. TSG is an important modulator of BMP-regulated induced collagen II and X expression and cartilage development and chondrocyte differentiation

TWSG1 Antigen Profile

Antigen Summary

May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development (By similarity).

Gene names and symbols associated with TWSG1

  • twisted gastrulation BMP signaling modulator 1a (twsg1a) antibody
  • twisted gastrulation BMP signaling modulator 1 (TWSG1) antibody
  • twisted gastrulation homolog 1 (Drosophila) (TWSG1) antibody
  • twisted gastrulation BMP signaling modulator 1 (Twsg1) antibody
  • 1810013J15Rik antibody
  • 9030422N06Rik antibody
  • AW552143 antibody
  • D17Ertd403e antibody
  • DKFZp469J051 antibody
  • fi23f01 antibody
  • Tsg antibody
  • tsga antibody
  • Twg antibody
  • TWSG1 antibody
  • wu:fi23f01 antibody

Protein level used designations for TWSG1

twisted gastrulation 1 , twisted gastrulation a , twisted gastrulation protein homolog 1-A , twisted gastrulation homolog 1 (Drosophila) , twisted gastrulation homolog 1 , Twisted gastrulation protein homolog 1 , twisted gastrulation protein homolog 1

84037 Danio rerio
455294 Pan troglodytes
705804 Macaca mulatta
100172557 Pongo abelii
65960 Mus musculus
57045 Homo sapiens
374024 Gallus gallus
490546 Canis lupus familiaris
537290 Bos taurus
363294 Rattus norvegicus
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