anti-Ubiquitin Specific Peptidase 21 (USP21) Antibodies

USP21 encodes a member of the C19 peptidase family, also known as family 2 of ubiquitin carboxy-terminal hydrolases. Additionally we are shipping USP21 Proteins (4) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
USP21 27005 Q9UK80
USP21 30941 Q9QZL6
USP21 688466 B2GUX4
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Top anti-USP21 Antibodies at antibodies-online.com

Showing 10 out of 106 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB Host: Rabbit  Target Name: Usp21  Sample Tissue: Mouse Brain lysates  Antibody Dilution: 1.0 µg/mL 100 μL 2 to 3 Days
$319.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL 6 to 8 Days
$484.00
Details
Human Goat Un-conjugated ELISA, WB   0.1 mg 6 to 7 Days
$286.39
Details
Human Mouse Un-conjugated ELISA, IHC, IHC (p), WB Anti-USP21 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1104946 dilution 20 ug/ml. Anti-USP21 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 20 ug/ml. 50 μg 11 to 14 Days
$639.83
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of RAW264.7 cells, using USP21 antibody. 100 μL 11 to 13 Days
$366.77
Details
Human Rabbit Un-conjugated WB Western blot analysis of hUSP21-L241 in NCI-H460 cell line lysates (35ug/lane) 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated IHC (p), WB Western Blot at 1:1000 dilution + human placenta lysate Lysates/proteins at 20 ug per lane. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. BC = breast carcinoma; HC = hepatocarcinoma. 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$581.17
Details

Top referenced anti-USP21 Antibodies

  1. Human Polyclonal USP21 Primary Antibody for IHC (p), ELISA - ABIN542899 : Hillier, Lennon, Becker, Bonaldo, Chiapelli, Chissoe, Dietrich, DuBuque, Favello, Gish, Hawkins, Hultman, Kucaba, Lacy, Le, Le, Mardis, Moore, Morris, Parsons, Prange, Rifkin, Rohlfing, Schellenberg et al.: Generation and analysis of 280,000 human expressed sequence tags. ... in Genome research 1997 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal USP21 Primary Antibody for ELISA - ABIN544824 : Gong, Kamitani, Millas, Yeh: Identification of a novel isopeptidase with dual specificity for ubiquitin- and NEDD8-conjugated proteins. in The Journal of biological chemistry 2000 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal USP21 Primary Antibody for IHC (p), ELISA - ABIN542799 : Puente, Sánchez, Overall, López-Otín: Human and mouse proteases: a comparative genomic approach. in Nature reviews. Genetics 2003 (PubMed)
    Show all 3 Pubmed References

More Antibodies against USP21 Interaction Partners

Human Ubiquitin Specific Peptidase 21 (USP21) interaction partners

  1. work identifies and validates USP21 as a PDAC oncogene

  2. Results from computational biology identified a cancer mutation that inactivates the nuclear export signals of the human deubiquitinase USP21, and leads to the aberrant accumulation of this protein in the nucleus.

  3. Data show that ubiquitin variants (Ubvs) that bind to USP2 or USP21 contain a similar core functional epitope, or "hot spot," consisting mainly of positions that are conserved as the wild type sequence, but also some positions that prefer mutant sequences.

  4. USP21 binds to the promoter region of IL-8 and mediates transcriptional initiation, which regulates the stem-cell like property of human renal cell carcinoma

  5. USP21 interacts with, deubiquitinates and stabilizes BRCA2 to promote efficient RAD51 loading at DNA double-strand breaks.

  6. a critical role of p38-mediated USP21 phosphorylation in regulating STING-mediated antiviral functions and identifies p38-USP21 axis as an important pathway that DNA virus adopts to avoid innate immunity responses.

  7. USP21 recruits and stabilises Gli1 at the centrosome.

  8. USP21 specifically regulates the Lys48-linked polyubiquitination and stability of NANOG

  9. Data show that SUMOylated BANP, E5R, and Nac1 (BEN) domain 3 (BEND3) stabilizes NoRC component TTF-1-interacting protein 5 (Tip5)via association with ubiquitin specific protease 21 (USP21) debiquitinase

  10. The protein stability of IL-33 is maintained by USP21 through deubiquitination

  11. Identification of the E3 deubiquitinase ubiquitin-specific peptidase 21 (USP21) as a positive regulator of the transcription factor GATA3

  12. Study observed a reduction in the number of A549 cells developing a primary cilium upon serum starvation when USP21 was depleted with two independent siRNA oligos.

  13. Study report that USP21 cleaves Ub polymers, and with reduced activity also targets ISG15, but is inactive against NEDD8.

  14. USP21 plays an important role in the down-regulation of TNFalpha-induced NF-kappaB activation through deubiquitinating RIP1.

Mouse (Murine) Ubiquitin Specific Peptidase 21 (USP21) interaction partners

  1. USP21 interacts with, deubiquitinates and stabilizes Nanog, and therefore maintains the protein level of Nanog in mouse embryonic stem cells to maintain stemness.

  2. USP21 recruits and stabilises Gli1 at the centrosome.

  3. Ubiquitin specific protease 21 is dispensable for normal development, hematopoiesis and lymphocyte differentiation

  4. Overexpression of USP21 inhibited RNA virus-induced RIG-I polyubiquitination and RIG-I-mediated interferon signaling, while USP21 deletion resulted in elevated RIG-I polyubiquitination, IRF3 phosphorylation, IFN production, and antiviral responses.

  5. USP21 plays an important role in the down-regulation of TNFalpha-induced NF-kappaB activation through deubiquitinating RIP1.

USP21 Antigen Profile

Protein Summary

This gene encodes a member of the C19 peptidase family, also known as family 2 of ubiquitin carboxy-terminal hydrolases. The encoded protein cleaves ubiquitin from ubiquitinated proteins for recycling in intracellular protein degradation. The encoded protein is also able to release NEDD8, a ubiquitin-like protein, from NEDD8-conjugated proteins. This gene has been referred to as USP16 and USP23 but is now known as USP21. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with USP21

  • ubiquitin specific peptidase 21 (USP21) antibody
  • ubiquitin specific peptidase 21 (Usp21) antibody
  • ESTM28 antibody
  • Usp16 antibody
  • USP21 antibody
  • Usp23 antibody
  • W53272 antibody

Protein level used designations for USP21

ubiquitin specific peptidase 21 , Ubiquitin specific peptidase 21 , NEDD8-specific protease , deubiquitinating enzyme 21 , ubiquitin carboxyl-terminal hydrolase 21 , ubiquitin specific protease 21 , ubiquitin thioesterase 21 , ubiquitin thiolesterase 21 , ubiquitin-specific processing protease 21 , ubiquitin-specific protease 16 , ubiquitin-specific-processing protease 21 , ubiquitin specific protease 23 , ubiquitin-specific protease 21

GENE ID SPECIES
469556 Pan troglodytes
478979 Canis lupus familiaris
719894 Macaca mulatta
100028924 Monodelphis domestica
100066197 Equus caballus
100152455 Sus scrofa
100413038 Callithrix jacchus
100431690 Pongo abelii
100483223 Ailuropoda melanoleuca
100601460 Nomascus leucogenys
27005 Homo sapiens
534273 Bos taurus
30941 Mus musculus
688466 Rattus norvegicus
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