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Deubiquitinating enzyme which may play an important role during spermatogenesis..
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Human Polyclonal USP42 Primary Antibody for ICC, IF - ABIN4364603
Hock, Vigneron, Carter, Ludwig, Vousden: Regulation of p53 stability and function by the deubiquitinating enzyme USP42. in The EMBO journal 2011
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USP42 overexpression could be a potential prognostic marker for GC, regulate the survival and invasive properties of GC, and may represent a novel therapeutic molecular target for this tumor.
a role for USP42 in regulating transcription by deubiquitylating histones
we report, for the first time, the identification of a RUNX1 (show RUNX1 Antibodies)-USP42 fusion transcript detected at diagnosis in a child with AML (show RUNX1 Antibodies) and del(5).
the function of USP42 is required to allow the rapid activation of p53 (show TP53 Antibodies)-dependent transcription and a p53 (show TP53 Antibodies)-dependent cell-cycle arrest in response to stress.
Northern blot analysis revealed that Usp42 is expressed mainly in brain, lung, thymus and testis, and at E10.5 the most during embryonic development.
Deubiquitinating enzyme which may play an important role during spermatogenesis.
ubiquitin specific peptidase 42
, ubiquitin carboxyl-terminal hydrolase 42-like
, ubiquitin specific protease 42
, deubiquitinating enzyme 42
, ubiquitin carboxyl-terminal hydrolase 42
, ubiquitin thioesterase 42
, ubiquitin thiolesterase 42
, ubiquitin-specific-processing protease 42