Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
UPK2 encodes one of the proteins of the highly conserved urothelium-specific integral membrane proteins of the asymmetric unit membrane which forms urothelium apical plaques in mammals. Additionally we are shipping Uroplakin 2 Proteins (8) and Uroplakin 2 Kits (4) and many more products for this protein.
Showing 10 out of 24 products:
Uroplakin II was immunopositive in 53% and 60% of urothelial carcinomas (UC) of the bladder and the ureter, respectively.
These results suggest that whereas GATA-3 and uroplakin II may be most useful in the diagnosis of urothelial carcinoma metastasis, p40 may be additionally suited as a prognostic marker.
UPII, GATA3, and p40, when used in combination, are highly sensitive in the differential diagnosis of invasive urothelial carcinoma.
UPII was highly specific/moderately sensitive for urothelial carcinoma. May be a potentially useful marker to identify urothelial lineage and help distinguish UC from prostate cancer or, in conjunction with GATA3, from metastatic breast cancer.
UPII demonstrates a significantly higher sensitivity than UPIII in conventional and variant urothelial carcinomas
Uroplakin II antibody BC21 demonstrated superior sensitivity and specificity in urothelial carcinoma, compared with uroplakin III, suggesting an advantage in differential diagnosis of urothelial carcinoma and in the detection of tumors of unknown origin.
combination of prostate stem cell antigen enhancer and uroplakin II promoter is feasible in constructing bladder cancer-specific vectors
study offers no definitive support for uroplakin II mutations causing human renal tract malformations
HNF4 positively regulates pUPII gene promoter activity.
all the major trans-regulatory elements required for bladder- and urethra-specific transcription are located in the 8.8 kb promoter upstream region
This gene encodes one of the proteins of the highly conserved urothelium-specific integral membrane proteins of the asymmetric unit membrane which forms urothelium apical plaques in mammals. The asymmetric unit membrane is believed to strengthen the urothelium by preventing cell rupture during bladder distention. The encoded protein is expressed in the peripheral blood of bladder cancer patients with transitional cell carcinomas.
, uroplakin II