anti-Voltage-Dependent Anion Channel 2 (VDAC2) Antibodies

VDAC2 encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane.

list all antibodies Gene Name GeneID UniProt
Anti-Human VDAC2 VDAC2 7417 P45880
Anti-Mouse VDAC2 VDAC2 22334 Q60930
Anti-Rat VDAC2 VDAC2 83531 P81155
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-VDAC2 Antibodies at antibodies-online.com

Showing 10 out of 80 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-VDAC2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  293T cell lysate VDAC2 is supported by BioGPS gene expression data to be expressed in HEK293T Host:  Rabbit  Target Name:  VDAC2  Sample Type:  Human Fetal Brain  Antibody Dilution:  1.0ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-VDAC2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Transfected 293T VDAC2 is supported by BioGPS gene expression data to be expressed in HEK293T WB Suggested Anti-VDAC2 Antibody    Titration:  1.6 ug/ml  Positive Control:  human cell lines 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, IP, IHC (p), ELISA, WB IHC-P Image VDAC2 antibody [C2C3], C-term detects VDAC2 protein at mitochondria on human normal liver by immunohistochemical analysis. Sample: Paraffin-embedded normal liver. VDAC2 antibody [C2C3], C-term , dilution: 1:250. IP Image VDAC2 antibody [C2C3], C-term immunoprecipitates VDAC2 protein in IP experiments. IP samples: HepG2 whole cell extract A. Control with 4 μg of preimmune Rabbit IgG B. Immunoprecipitation of VDAC2 protein by 4 μg VDAC2 antibody [C2C3], C-term , 10 % SDS-PAGE The immunoprecipitated VDAC2 protein was detected by VDAC2 antibody [C2C3], C-term , diluted at 1:1000. [EasyBlot anti-rabbit IgG  was used as a secondary reagent] 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Goat Un-conjugated ELISA, WB ABIN185206 (0.3 ug/ml) staining of Human Testis lysate (35 ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. ABIN185206 (1 µg/mL) staining of Human Brain (Cerebellum) lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$358.02
Details
Human Goat Un-conjugated ELISA, WB ABIN185705 (0.3 ug/ml) staining of Human Heart lysate (35 ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$358.02
Details
Human Mouse Un-conjugated WB Western Blot analysis of VDAC2 expression in transfected 293T cell line by VDAC2 monoclonal antibody (M01), clone 3D2. Lane 1: VDAC2 transfected lysate(31.6 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Goat Un-conjugated ELISA, IHC, IHC (p), WB Human Heart (formalin-fixed, paraffin-embedded) stained with VDAC2 antibody ABIN337065 at 2.5-5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$484.00
Details
Human Goat Un-conjugated ELISA, WB Western Blot: VDAC2 Antibody [ABIN268631] - (0.3ug/ml) staining of Human Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Western Blot: VDAC2 Antibody [ABIN268631] - (1 ug/ml) staining of human brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Human Goat Un-conjugated ELISA, WB Western Blot: VDAC2 Antibody [NBP1-68794] - (0.3ug/ml) staining of Human Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details

Top referenced anti-VDAC2 Antibodies

  1. Human Polyclonal VDAC2 Primary Antibody for ELISA, WB - ABIN268631 : Blachly-Dyson, Zambronicz, Yu, Adams, McCabe, Adelman, Colombini, Forte: Cloning and functional expression in yeast of two human isoforms of the outer mitochondrial membrane channel, the voltage-dependent anion channel. in The Journal of biological chemistry 1993 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal VDAC2 Primary Antibody for ELISA, WB - ABIN4251059 : Chandra, Choy, Daniel, Tang: Bax-dependent regulation of Bak by voltage-dependent anion channel 2. in The Journal of biological chemistry 2005 (PubMed)

  3. Cow (Bovine) Polyclonal VDAC2 Primary Antibody for IHC, WB - ABIN2776154 : Hrabakova, Kollareddy, Tyleckova, Halada, Hajduch, Gadher, Kovarova: Cancer cell resistance to aurora kinase inhibitors: identification of novel targets for cancer therapy. in Journal of proteome research 2013 (PubMed)
    Show all 2 Pubmed References

More Antibodies against VDAC2 Interaction Partners

Human Voltage-Dependent Anion Channel 2 (VDAC2) interaction partners

  1. VDAC2 ensures mitochondria-specific membrane association of Bax (show BAX Antibodies) and in the absence of VDAC2 Bax (show BAX Antibodies) localizes towards other cell compartments. Bax (show BAX Antibodies) retrotranslocation is also regulated by nucleotides and calcium ions, suggesting a potential role of the transport of these ions through VDAC2 in Bax (show BAX Antibodies) retrotranslocation.

  2. High methylation of the VDAC2 promoter CpGs in men with asthenospermia

  3. Chinese men carrying VDAC2 variants may have a decreased or increased risk of abnormal semen parameters associated with male infertility.

  4. The works available on VDAC cysteines support the notion that VDAC1 (show VDAC1 Antibodies), VDAC2, and VDAC3 (show VDAC3 Antibodies) proteins are paralogs with a similar pore-function and slightly different, but important, ancillary biological functions. (Review)

  5. The evolutionary demand for the NTE (show PNPLA6 Antibodies) in the presence of cysteines clearly emerges from our biochemical and functional studies, providing insight into factors that functionally demarcate hVDAC-2 from the other VDACs.

  6. Motifs of VDAC2 required for mitochondrial Bak (show BAK1 Antibodies) import and tBid-induced apoptosis.

  7. Results show that in thyroid tumours and cell lines, VDAC2 is upregulated and BAK1 (show BAK1 Antibodies) downregulated. Also, transient knockdown of VDAC2 promoted upregulation of the BAK1 (show BAK1 Antibodies) expression, and increased susceptibility to sorafenib treatment.

  8. These data suggest that an interaction between Mcl-1 (show MCL1 Antibodies) and VDAC promotes lung cancer cell migration by a mechanism that involves Ca(2 (show CA2 Antibodies)+)-dependent reactive oxygen species production.

  9. RACK1 (show GNB2L1 Antibodies) plays an antiapoptotic role during IBDV infection via interaction with VDAC2 and VP5.

  10. GSK-3beta translocates from the cytosol to mitochondria in a kinase activity- and VDAC2-dependent manner in which an N-terminal domain of GSK-3beta may function as a mitochondrial targeting sequence

Mouse (Murine) Voltage-Dependent Anion Channel 2 (VDAC2) interaction partners

  1. an important MYBL2 (show MYBL2 Antibodies)-VDAC2-BECN1 (show BECN1 Antibodies)-BCL2L1 (show BCL2L1 Antibodies) pathway linking autophagy suppression in the developing ovary, is reported.

  2. Motifs of VDAC2 required for mitochondrial Bak (show BAK1 Antibodies) import and tBid-induced apoptosis.

  3. Bax (show BAX Antibodies) localizes to the mitochondrial outer membrane via alternate mechanisms, either constitutively via an interaction with VDAC2 or after activation via interaction with Bcl-2 (show BCL2 Antibodies) family proteins.

  4. Bcl-xL (show BCL2L1 Antibodies) interacts functionally with VDAC1 (show VDAC1 Antibodies) and -3 but not VDAC2.

  5. VDAC2 acts as a crucial component in mitochondrial apoptosis by allowing the mitochondrial recruitment of BAK (show BAK1 Antibodies), thereby controlling tBID-induced OMM permeabilization and cell death.

  6. VDAC2 regulates the activity of BAK (show BAK1 Antibodies) and provides a connection between mitochondrial physiology and the core apoptotic pathway

  7. Vdacs are dispensable for both MPT and Bcl-2 (show BCL2 Antibodies) family member-driven cell death.

  8. Genetic depletion of Vdac2 in the thymus resulted in excessive cell death & hypersensitivity to diverse death stimuli including engagement of the T cell receptor. The VDAC2-BAK (show BAK1 Antibodies) axis governs the homeostasis of thymocytes.

Cow (Bovine) Voltage-Dependent Anion Channel 2 (VDAC2) interaction partners

  1. ENO1, VDAC2, and UQCRC2 (show UQCRC2 Antibodies) were significantly correlated with individual fertility in bulls.

  2. Results describe the expression of voltage-dependent anion channel isoforms in rat, bovine, and chicken brain mitochondria, and suggest that the nature of hexokinase binding site is not determined by the expression of a single VDAC isoform.

  3. VDAC2 and VDAC3 (show VDAC3 Antibodies) might have an alternative structural organization and different functions in outer dense fibers (show ODF1 Antibodies) than in mitochondria

  4. Confirm the localisation of VDAC2 in the acrosomal region of bovine spermatozoa using immunoelectron microscopy.

  5. The present study is the first work to report the purification and characterization of VDAC2 from a mammalian tissue.

Zebrafish Voltage-Dependent Anion Channel 2 (VDAC2) interaction partners

  1. These findings demonstrate a critical modulatory role for VDAC2-dependent mitochondrial Ca(2 (show CA2 Antibodies)+) uptake in the regulation of cardiac rhythmicity.

  2. Data indicate the structure of voltage-dependent anion channel 2 zfVDAC2 at 2.8 A resolution, revealing a crystallographic dimer.

Pig (Porcine) Voltage-Dependent Anion Channel 2 (VDAC2) interaction partners

  1. an important MYBL2 (show MYBL2 Antibodies)-VDAC2-BECN1 (show BECN1 Antibodies)-BCL2L1 (show BCL2L1 Antibodies) pathway linking autophagy suppression in the developing ovary, is reported.

  2. Data confirm the synthesis of VDAC1 (show VDAC1 Antibodies) and 2 subtypes in GV (germinal vesicle) and MII (meiosis II) stage porcine oocytes as well as their protein expression.

Arabidopsis thaliana Voltage-Dependent Anion Channel 2 (VDAC2) interaction partners

  1. AtVDAC2 has a main function in mitochondria

  2. VDAC2 and VDAC4 are important for leaf development, the mitochondrial membrane potential, and pollen development.

VDAC2 Antigen Profile

Protein Summary

This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1, 2, 12 and 21, and alternative splicing results in multiple transcript variants.

Gene names and symbols associated with VDAC2

  • voltage dependent anion channel 2 (VDAC2) antibody
  • voltage-dependent anion channel 2 (Vdac2) antibody
  • voltage-dependent anion channel 2 (vdac2) antibody
  • voltage-dependent anion channel 2 S homeolog (vdac2.S) antibody
  • voltage dependent anion channel 2 (Vdac2) antibody
  • ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 2 antibody
  • ATVDAC2 antibody
  • K9I9.6 antibody
  • K9I9_6 antibody
  • mVDAC2 antibody
  • mVDAC6 antibody
  • POR antibody
  • VDAC2 antibody
  • Vdac6 antibody
  • voltage dependent anion channel 2 antibody
  • wu:fa01a08 antibody
  • wu:fa98a10 antibody
  • wu:fb50g11 antibody
  • zgc:55795 antibody
  • zgc:77621 antibody

Protein level used designations for VDAC2

outer mitochondrial membrane protein porin 2 , voltage-dependent anion-selective channel protein 2 , VDAC-2 , VDAC-6 , voltage-dependent anion-selective channel protein 6 , B36-VDAC , voltage-dependent anion channel 2 , outer mitochondrial membrane protein porin

GENE ID SPECIES
7417 Homo sapiens
22334 Mus musculus
83531 Rattus norvegicus
282120 Bos taurus
322126 Danio rerio
395498 Gallus gallus
397659 Sus scrofa
479255 Canis lupus familiaris
548947 Xenopus (Silurana) tropicalis
100009473 Oryctolagus cuniculus
738876 Pan troglodytes
100528960 Ictalurus punctatus
836886 Arabidopsis thaliana
734449 Xenopus laevis
100540440 Meleagris gallopavo
101092793 Felis catus
100723838 Cavia porcellus
101865627 Macaca fascicularis
Did you look for something else?