Von Willebrand Factor (VWF) ELISA Kits

Human Von Willebrand Factor (VWF) interaction partners

1. Different patterns of VWF multimer loss were seen in heart failure patients treated with implantation of left ventricular assist device and total artificial heart, which may contribute to bleeding patterns.

2. Complex VWF-ADAMTS13 (show ADAMTS13 ELISA Kits)-mediated mechanisms disturb haemostasis in inflammatory bowel disease.

3. PP2B (show CAN ELISA Kits)-Aalpha-Munc18c complex supports agonist-induced VWF secretion by HUVECs.

4. Deficiency of the von Willebrand factor-cleaving protease ADAMTS13 (show ADAMTS13 ELISA Kits) is central to the pathophysiology of thrombotic thrombocytopenic purpura. Reviewed is the evidence emerged from epidemiological studies of an inverse relationship between the plasma levels of ADAMTS13 (show ADAMTS13 ELISA Kits) and the risk of acute coronary syndrome. [review]

5. genetic variation of vWF V1565L polymorphism modulates ADAMTS13 (show ADAMTS13 ELISA Kits) activity.

6. Plasma levels of VWF antigen and activity are significantly increased with concomitant reduction in plasma ADAMTS13 (show ADAMTS13 ELISA Kits) activity in patients with subarachnoid haemorrhage.

7. Report a diagnostic algorithm that can reliably identify pathogenic variants of factor 8/9 and von Willebrand factor and diagnose patients with hemophilia A, hemophilia B or von Willebrand disease.

8. analysis of an artificial botrocetin that can inhibit the VWF-GPIb interaction

9. VWF binding to MMRN1 (show MMRN1 ELISA Kits) was enhanced by shear exposure and ristocetin, and required VWF A1A2A3 region, specifically the A1 and A3 domains.

10. coronary thrombi in STEMI patients resistant to fibrinolysis are characterised by higher fibrin, P-selectin (show SELP ELISA Kits) and VWF content than lysis-sensitive thrombi

Pig (Porcine) Von Willebrand Factor (VWF) interaction partners

1. In conclusion, endothelial vWF knockdown prevented angiotensin II-induced ET-1 (show EDN1 ELISA Kits) upregulation through attenuation of NOX-mediated O2- production.

2. alterations in glycosylation of vWF and other adhesion proteins associated with the targeting of the alpha1,3-Gal (show GAL ELISA Kits)-epitope in mutant swine may have salutatory effects on the primate platelet activation observed in these xenografts.

Cow (Bovine) Von Willebrand Factor (VWF) interaction partners

1. Hemodynamic activation of vWF and increased plasma ADAMTS-13 (show ADAMTS13 ELISA Kits) may have contributed to reduced high-molecular-weight vWF multimers and impairment of the vWF-platelet aggregation pathway during mechanical circulatory support.

2. both the gpIb-VWF interaction and the integrin alpha(2 (show ITGA2 ELISA Kits))beta(1)-collagen interaction contribute to platelet adhesion under high shear stress; integrin alpha(II (show GSTA3 ELISA Kits))beta(1) makes a greater contribution to adhesion to type I collagen because less VWF is bound

Mouse (Murine) Von Willebrand Factor (VWF) interaction partners

1. Type 2N von Willebrand disease variants were associated with decreased VWF secretion and impaired factor VIII binding/stability.

2. identify a critical role for VWF in cerebral inflammation and blood-brain barrier damage after intracerebral haemorrhage

3. The low-molecular-weight heparin (LMWH) Tinzaparin inhibited Von Willebrand factor (VWF) fiber formation and vessel occlusion in tumor vessels by blocking thrombin (show F2 ELISA Kits)-induced endothelial cells (ECs) activation and vascular endothelial growth factor-A (VEGF-A (show VEGFA ELISA Kits))-mediated VWF release.

4. In a laser injury-induced thrombosis model, P-selectin (show SELP ELISA Kits) modulates thrombus propagation independently of VWF and TSP1 (show GZMA ELISA Kits)

5. Refrigeration-induced binding of VWF to platelets facilitates their rapid clearance by inducing GPIbalpha (show GP1BA ELISA Kits)-mediated signaling.

6. BLOC-2 (show HPS6 ELISA Kits) subunit HPS6 (show HPS6 ELISA Kits) deficiency affects the tubulation and secretion of von Willebrand factor from mouse endothelial cells

7. A novel single-domain antibody against von Willebrand factor A1 domain that interferes with VWF-platelet interactions in vivo. By using this sdAb, show that the A1 domain is pertinent to the participation of VWF in the inflammatory response.

8. These experiments delineate an unexpected pathway in which microbiota-triggered TLR2 signaling alters the synthesis of proadhesive VWF by the liver endothelium and favors platelet integrin-dependent thrombus growth.

9. ADAMTS13 (show ADAMTS13 ELISA Kits) controls vascular remodeling by modifying VWF reactivity during stroke recovery.

10. these novel findings support the hypothesis that conformation of the VWF A domains plays a critical role in modulating macrophage-mediated clearance of VWF in vivo.