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WRNIP1 Proteins

Werner's syndrome is a rare autosomal recessive disorder characterized by accelerated aging that is caused by defects in the Werner syndrome ATP-dependent helicase gene (WRN).

3 results:

Werner Helicase Interacting Protein 1 (WRNIP1) (AA 1-665) protein (His tag) Protein

WRNIP1 Reactivity: Human Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3075618
$10,832.86
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 60 Business Days

Werner Helicase Interacting Protein 1 (WRNIP1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag) Protein

WRNIP1 Reactivity: Human Source: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
Catalog No. ABIN2715072
$932.80
Plus shipping costs $45.00 and $24.00 dry ice
20 μg
local_shipping Shipping to: United States
Will be delivered in 11 Business Days

Werner Helicase Interacting Protein 1 (WRNIP1) (AA 1-660) protein (His tag) Protein

WRNIP1 Reactivity: Rat Source: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1624852
$3,916.00
Plus shipping costs $45.00
1 mg
local_shipping Shipping to: United States
Delivery in 57 to 68 Business Days
  • Type Protein
    • Protein
  • Target Werner Helicase Interacting Protein 1 (WRNIP1)
    • Werner Helicase Interacting Protein 1 (WRNIP1)
    • Hemagglutinin (HA)
    • Ribosome Binding Factor A (RBFA)
    • Tumor Necrosis Factor alpha (TNF)
    • S-Adenosyl-Methionine Synthase (METK)
    • Interleukin 6 (IL6)
    • Interferon gamma (IFNG)
    • Hemoglobin beta (HBB)
    • Triosephosphate Isomerase 1 (TPI1)
    • Thymidylate Kinase (Tmk)
    • Interleukin 4 (IL4)
    • Interleukin 1, beta (IL1B)
    • Interleukin 2 (IL2)
    • Uracil-DNA Glycosylase (UNG)
    • Fibroblast Growth Factor 2 (Basic) (FGF2)
    • Growth Hormone 1 (GH1)
    • Lipoyl synthase lipA
    • Interleukin 10 (IL10)
    • KIT Ligand (KITLG)
    • Malate Dehydrogenase (MDH)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Epidermal Growth Factor (EGF)
    • Leptin (LEP)
    • Interleukin 8 (IL8)
    • Interleukin 3 (IL-3)
    • Myoglobin (MB)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1)
    • Hemoglobin, alpha 1 (HBA1)
    • phosphatidylserine Decarboxylase (PISD)
    • Interleukin 1 alpha (IL1A)
    • Prolactin (PRL)
    • CD40 Ligand (CD40LG)
    • Interleukin 13 (IL13)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Chemokine (C-X-C Motif) Ligand 12 (CXCL12)
    • Albumin (ALB)
    • Aspartate Carbamoyltransferase (PYRB)
    • Interleukin 15 (IL15)
    • Phosphoglucosamine Mutase (GLMM)
    • Porphobilinogen Deaminase (HEMC)
    • beta-2-Microglobulin (B2M)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Gp120
    • Adiponectin (ADIPOQ)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Interleukin 33 (IL33)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • Fibroblast Growth Factor 1 (Acidic) (FGF1)
    • Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1)
  • Application
    • ELISA
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Protein Interaction (PI)
    • SDS-PAGE (SDS)
    • Standard (STD)
    • Western Blotting (WB)
    • Crystallization (Crys)
  • Reactivity
    • Human
    • Rat
  • Images available
  • Host
    • HEK-293 Cells
    • Insect Cells
    • Yeast
  • Binding Specificity
    • AA 1-660
    • AA 1-665
    • Transcript Variant 2
  • Conjugate
    • Un-conjugated
    • His tag
    • Myc-DYKDDDDK Tag
  • Protein Type
    • Recombinant
  • Format
    • Liquid
    • Lyophilized

WRNIP1 Protein Profile

Protein Summary

Werner's syndrome is a rare autosomal recessive disorder characterized by accelerated aging that is caused by defects in the Werner syndrome ATP-dependent helicase gene (WRN). The protein encoded by this gene interacts with the exonuclease-containing N-terminal portion of the Werner protein. This protein has a ubiquitin-binding zinc-finger domain in the N-terminus, an ATPase domain, and two leucine zipper motifs in the C-terminus. It has sequence similarity to replication factor C family proteins and is conserved from E. coli to human. This protein likely accumulates at sites of DNA damage by interacting with polyubiquinated proteins and also binds to DNA polymerase delta and increases the initiation frequency of DNA polymerase delta-mediated DNA synthesis. This protein also interacts with nucleoporins at nuclear pore complexes. Two transcript variants encoding different isoforms have been isolated for this gene.

Gene names and symbols associated with WRNIP1

  • Werner helicase interacting protein 1 (WRNIP1) antibody
  • Werner helicase interacting protein 1 L homeolog (wrnip1.L) antibody
  • Werner helicase interacting protein 1 (wrnip1) antibody
  • ATPase WRNIP1 (EDI_075920) antibody
  • ATPase WRNIP1 (CpipJ_CPIJ017857) antibody
  • ATPase WRNIP1 (PITG_07216) antibody
  • ATPase WRNIP1 (VDBG_02914) antibody
  • Werner helicase interacting protein 1 (Wrnip1) antibody
  • ATPase WRNIP1 (PGTG_08805) antibody
  • 4833444L21Rik antibody
  • bA420G6.2 antibody
  • RP11-420G6.2 antibody
  • Whip antibody
  • Wrnip antibody
  • wrnip1 antibody
  • zgc:85976 antibody

Protein level used designations for WRNIP1

ATPase WRNIP1 , Werner helicase interacting protein 1 , Werner helicase-interacting protein 1 , putative helicase RUVBL , Werner helicasae interacting protein 1 , Werner syndrome homolog interacting protein , werner helicase-interacting protein 1

GENE ID SPECIES
788824 Bos taurus
462392 Pan troglodytes
707250 Macaca mulatta
734231 Xenopus laevis
56897 Homo sapiens
405856 Danio rerio
5882536 Entamoeba dispar SAW760
6052914 Culex quinquefasciatus
9471556 Phytophthora infestans T30-4
9532917 Verticillium alfalfae VaMs.102
78903 Mus musculus
282835 Rattus norvegicus
395089 Gallus gallus
100158593 Xenopus (Silurana) tropicalis
10529992 Puccinia graminis f. sp. tritici CRL 75-36-700-3
100595079 Nomascus leucogenys
100155921 Sus scrofa

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