WTIP Proteins
Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration.
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Wilms Tumor 1 Interacting Protein (WTIP) (AA 1-430) protein (His tag) Protein
Wilms Tumor 1 Interacting Protein (WTIP) protein (Myc-DYKDDDDK Tag) Protein
WTIP Protein Profile
Protein Summary
Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA)-mediated gene silencing. Negatively regulates Hippo signaling pathway and antagonizes phosphorylation of YAP1. Acts as a transcriptional corepressor for SNAI1 and SNAI2/SLUG-dependent repression of E-cadherin transcription. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. May monitor slit diaphragm protein assembly, a specialized adherens junction characteristic of podocytes. In case of podocyte injury, it shuttles into the nucleus and acts as a transcription regulator that represses WT1- dependent transcription regulation, thereby translating changes in slit diaphragm structure into altered gene expression and a less differentiated phenotype.
Gene names and symbols associated with WTIP
- WT1 interacting protein (Wtip) antibody
- WT1 interacting protein (WTIP) antibody
- WT1 interacting protein (wtip) antibody
- Wilms tumor 1 interacting protein (WTIP) antibody
- WT1 interacting protein L homeolog (wtip.L) antibody
- WT1-interacting protein (Wtip) antibody
- RGD1306411 antibody
- si:ch211-79l17.3 antibody
Protein level used designations for WTIP
WT1-interacting protein , Wilms tumor protein 1-interacting protein , Wilms tumor protein 1-interacting protein homolog , WT1-interacting protein homolog , Wilms tumor 1 interacting protein , xWtip
| GENE ID | SPECIES |
|---|---|
| 361552 | Rattus norvegicus |
| 505059 | Bos taurus |
| 566046 | Danio rerio |
| 747259 | Pan troglodytes |
| 769595 | Gallus gallus |
| 126374 | Homo sapiens |
| 100127345 | Xenopus laevis |
| 101543 | Mus musculus |
Did you look for something else?
- Wilms Tumor 1 Associated Protein Proteins
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- Wingless-Type MMTV Integration Site Family, Member 10B Proteins
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- Wingless-Type MMTV Integration Site Family, Member 2B Proteins
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- Wingless-Type MMTV Integration Site Family, Member 5B Proteins
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- Wingless-Type MMTV Integration Site Family, Member 7A Proteins
- Wingless-Type MMTV Integration Site Family, Member 7B Proteins
- Wingless-Type MMTV Integration Site Family, Member 8A Proteins
- Wingless-Type MMTV Integration Site Family, Member 9A Proteins
- Wingless-Type MMTV Integration Site Family, Member 9B Proteins
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