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YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. Additionally we are shipping YY1 Transcription Factor Proteins (8) and YY1 Transcription Factor Kits (7) and many more products for this protein.
Showing 10 out of 147 products:
Human Polyclonal YY1 Primary Antibody for ChIP, WB - ABIN3434034
Baritaki, Huerta-Yepez, Sakai, Spandidos, Bonavida: Chemotherapeutic drugs sensitize cancer cells to TRAIL-mediated apoptosis: up-regulation of DR5 and inhibition of Yin Yang 1. in Molecular cancer therapeutics 2007
Show all 6 Pubmed References
Human Monoclonal YY1 Primary Antibody for WB - ABIN1882292
Burkard, Planyavsky, Kaupe, Breitwieser, Bürckstümmer, Bennett, Superti-Furga, Colinge: Initial characterization of the human central proteome. in BMC systems biology 2011
Show all 4 Pubmed References
Human Polyclonal YY1 Primary Antibody for IHC, IHC (p) - ABIN4366543
Bevelacqua, Bevelacqua, Candido, Skarmoutsou, Amoroso, Guarneri, Strazzanti, Gangemi, Mazzarino, DAmico, McCubrey, Libra, Malaponte: Nectin like-5 overexpression correlates with the malignant phenotype in cutaneous melanoma. in Oncotarget 2012
Show all 2 Pubmed References
Human Polyclonal YY1 Primary Antibody for ICC, IF - ABIN4366542
Soares, Cagnin, Chemello, Silvestrin, Musaro, De Pitta, Lanfranchi, Sandri: Involvement of microRNAs in the regulation of muscle wasting during catabolic conditions. in The Journal of biological chemistry 2014
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Human Monoclonal YY1 Primary Antibody for IF, IHC (p) - ABIN563397
Shin, Lee, Park, Kim, Ryu, Park, Yu, Jang: Gene expression profiling of human hepatoblastoma using archived formalin-fixed and paraffin-embedded tissues. in Virchows Archiv : an international journal of pathology 2011
Human Polyclonal YY1 Primary Antibody for WB - ABIN521441
Westendorp, Major, Nader, Salih, Leenen, Tuana: The E2F6 repressor activates gene expression in myocardium resulting in dilated cardiomyopathy. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012
YY1 is essential for Xenopus development in neural ectoderm differentiation, neural crest specification and directing neural crest mesenchyme formation by blocking slug
Yin Yang 1 transcription factor assembly into messenger ribonucleoprotein particles requires direct RNA binding activity
Results show that the YY1-RNA interaction is highly stable, and that YY1 possesses the ability to interact with structurally divergent RNA substrates.
results suggest that YY1a regulates PS receptor expression that linked to function of PSR (show JMJD6 Antibodies)-phagocyte mediated apoptotic cell engulfment during development
YY1 promotes zebrafish liver steatosis and lipotoxicity by inhibiting CHOP-10 (show DDIT3 Antibodies) expression.
Study demonstrated that beta-arrestin1 (show ARRB1 Antibodies) is critically involved in zebrafish primitive hematopoiesis, where beta-arrestin1 (show ARRB1 Antibodies) binds to and sequesters the PcG recruiter YY1, thus relieving PcG-mediated repression of cdx4-hox (show MSH2 Antibodies) pathway.
Results show that histone deacetylase 1 (HDAC1 (show HDAC1 Antibodies)) expression was positively correlated with YY1 transcription factor (YY1) in hepatocellular carcinoma (HCC (show FAM126A Antibodies)) cell lines and primary tumor tissues.
Authors found that YY1 and STAT1 (show STAT1 Antibodies) were upregulated in ox-LDL-stimulating macrophages followed by translocation in the nucleus and binding to the transcriptional promoter region of miR (show MLXIP Antibodies)-29a, thus leading to the increase of miR (show MLXIP Antibodies)-29a expression.
results support a model in which YY1 acts as an architectural protein to connect developmentally regulated looping interactions; the location of YY1-mediated interactions may be demarcated in development by a preexisting topological framework created by constitutive CTCF (show CTCF Antibodies)-mediated interactions.
High expression of nuclear YY1 was significantly associated with higher AJCC stage and small vessel invasion.
This is the first report on the status of YY1 T372R in insulinoma (show RPS15 Antibodies) cases of Indian origin.
YY1 promotes proliferation and migration with suppression of apoptosis via directly inhibiting MYCT1 (show MYCT1 Antibodies) in laryngeal cancer cells, suggesting that YY1 is a useful target as a potential oncogene (show RAB1A Antibodies) in laryngeal cancer development and progression.
These data suggested that YY1 may be important for apoptosis induction via the regulation of Fas (show FAS Antibodies) during sepsis. Therefore, Fas (show FAS Antibodies) may be a potential therapeutic target to prevent MOD (show MOD(MDG4) Antibodies) through regulation of YY1 expression. Furthermore, YY1 and Fas (show FAS Antibodies) expression in PBMCs may be used to as prognostic markers.
Study shows that the ubiquitously expressed transcription factor Yin Yang 1 (YY1) contributes to enhancer-promoter structural interactions in a manner analogous to DNA interactions mediated by CTCF (show CTCF Antibodies).
YY1 was over-expressed in RA which can bind to the promotor of IL-6 (show IL6 Antibodies) to introduce IL-6 (show IL6 Antibodies) expression, contributing to the inflammation of RA via stimulation of Th17 differentiation.
YY1 promotes apoptosis via upregulating Bax (show BAX Antibodies) transcription and subsequent activation of Bax (show BAX Antibodies) by translocation from the cytosol to the mitochondrial membrane.
These observations support a role for YY1 meditating and/or regulating the interaction of OCT4 (show POU5F1 Antibodies) and SOX2 (show SOX2 Antibodies) at a posttranscriptional level.
these results demonstrate that YY1 overexpression is sufficient to maintain a Cardiac Progenitor Cell phenotype.
these results suggested that the basal promoter activity of the mIRF-3 gene is regulated by transcription factors Egr2 (show EGR2 Antibodies) and YY1 in NIH3T3 cells
DNA binding domain of YY1 is necessary for X-chromosome inactivation in activated B cells, as ex-vivo YY1 deletion results in loss of inactive X (Xi) chromosome heterochromatin marks and up-regulation of X-linked genes.
Transcriptome analysis revealed that YY1 is required for mitochondrial gene expression, and ultrastructural analysis confirmed compromised mitochondrial integrity in the mutant intestine.
regulates broad general processes throughout all stages of B-cell differentiation: normally activates genes involved in mitochondrial bioenergetics; normally down-regulates genes involved in transcription, mRNA splicing, NF-kappaB (show NFKB1 Antibodies) signaling pathways, the AP-1 (show JUN Antibodies) transcription factor network, chromatin remodeling, cytokine signaling pathways, cell adhesion, and cell proliferation
Results indicate that YY1 plays an important role in regulating the balance between dark zone and light zone cells in germinal center (GCs (show UGCG Antibodies)) and between survival and death of GC B (show NPR2 Antibodies) cells.
YY1 is required for germinal center B cell development.
Dp71 (show DMD Antibodies) expression in hepatic cells is carried out, in part, by YY1-, Sp1 (show SP1 Antibodies)- and Sp3 (show SP3 Antibodies)-mediated transcription from the Dp71 (show DMD Antibodies) promoter.
this study shows that YY1 regulates the formation of terminal-effector CD8 (show CD8A Antibodies)+ T cell fates
YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.
YY1 transcription factor
, YY1 transcription factor, like
, transcription factor YY1
, Yin Yang 1
, INO80 complex subunit S
, Yin and Yang 1 protein
, delta transcription factor
, transcriptional repressor protein YY1
, GLI-Krupple related protein
, UCR-motif DNA-binding protein
, UCRBP transcription factor
, yin and yang 1