Zw10 Kinetochore Protein Proteins (ZW10)

ZW10 encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. Additionally we are shipping Zw10 Kinetochore Protein Antibodies (54) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ZW10 9183 O43264
ZW10 363059 Q4V8C2
Mouse ZW10 ZW10 26951 O54692
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Top Zw10 Kinetochore Protein Proteins at

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 11 Days
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days

ZW10 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Rat (Rattus)

More Proteins for Zw10 Kinetochore Protein (ZW10) Interaction Partners

Human Zw10 Kinetochore Protein (ZW10) interaction partners

  1. The RZZ complex was purified to homogeneity and subjected to systemic crystallization.

  2. hZwint-1 bridges the inner and outer kinetochore: identification of the kinetochore localization domain and the hZw10-interaction domain

  3. Overexpression, microinjection and knockdown experiments revealed that ZW10 is involved in membrane trafficking between the endoplasmic reticulum and Golgi

  4. show that ZW10 interacting protein-1(Zwint-1) is required and is sufficient for kinetochore localization of Zeste White 10 (ZW10) in HeLa cells

  5. ZW10 serves as a general regulator of dynein function throughout the cell cycle.

  6. RINT-1 coordinates the localization and function of ZW10 by serving as a link between ZW10 and the SNARE complex comprising syntaxin 18.

  7. targeting of ZW10 to the perinuclear Golgi region was found to depend on the perinuclear accumulation of dynactin

  8. RNAi-mediated depletion of ZW10 markedly-reduced congression efficiency.

  9. Rab6 regulates distinct Golgi trafficking pathways involving two separate protein complexes: ZW10/RINT-1 and COG.

  10. Accumulation of ZW10 at tensionless kinetochores stems from a 4-fold reduction of kinetochore turnover rate and requires aurora B kinase activity.

  11. Stable hZW10 kinetochore residency at prometaphase kinetochores is dependent on its interaction with hZwint-1, and is essential for mitotic checkpoint arrest.

  12. The interaction between ZW10 and dynamitin showed that the N-terminal region of ZW10 is the major binding site for dynamitin and, like full-length ZW10, could move along microtubules to the centrosomal area in a dynein-dynactin-dependent manner.

  13. Results together suggest that NAG links between p31 and ZW10-RINT-1 and is involved in Golgi-to-ER transport.

Zw10 Kinetochore Protein (ZW10) Protein Profile

Protein Summary

This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. This protein is an essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis.

Gene names and symbols associated with ZW10

  • zw10 kinetochore protein (ZW10)
  • zw10 kinetochore protein (Zw10)
  • 6330566F14Rik protein
  • HZW10 protein
  • KNTC1AP protein
  • MmZw10 protein

Protein level used designations for ZW10

ZW10 homolog, centromere/kinetochore protein , ZW10, kinetochore associated, homolog , centromere/kinetochore protein zw10 homolog , zeste white 10 homolog

9183 Homo sapiens
363059 Rattus norvegicus
26951 Mus musculus
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