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The enzyme encoded by GGT1 catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. Additionally we are shipping gamma Glutamyltransferase 1 Antibodies (140) and gamma Glutamyltransferase 1 Proteins (18) and many more products for this protein.
Showing 10 out of 60 products:
Human GGT1 ELISA Kit for Sandwich ELISA - ABIN416980
Wu, Xie, Han, Ye, Weiel, Li, Blanco, Ahn, Olsen, Putterman, Saxena, Mohan: Metabolic disturbances associated with systemic lupus erythematosus. in PLoS ONE 2012
Show all 2 Pubmed References
Mouse (Murine) GGT1 ELISA Kit for Competition ELISA - ABIN627888
Zhang, Uaesoontrachoon, Shaughnessy, Das, Rayavarapu, Brown, Ray, Nagaraju, van den Anker, Hoffman, Hathout: The use of urinary and kidney SILAM proteomics to monitor kidney response to high dose morpholino oligonucleotides in the mdx mouse. in Toxicology reports 2015
The probe exhibits very high selectivity and sensitivity toward GGT activity from in vitro to in vivo and in clinical samples, which offers a promising tool for investigations of the GGT-overexpressing related biological process including tumor diagnosis and prognosis in living organisms.
both tumor GGT and serum GGT are poor prognostic factors in gastric cancer
The GPR (show ALDH18A1 ELISA Kits) could be used as a non-invasive marker to predict liver fibrosis and cirrhosis in CHB-NAFLD (show TSC2 ELISA Kits) individuals.
This study demonstrated a positive association between serum GGT levels and LV diastolic dysfunction and LV hypertrophy in a large cohort of middle-aged men and women independent of potential confounders.
we found that serum exosomal GGT activity was significantly higher in prostate cancer (PC), patients than in benign prostatic hyperplasia (BPH) patients. In support of this finding, immunohistochemical analysis showed increased GGT1 expression in PC tissues compared with BPH tissues. Our results suggest that serum exosomal GGT activity could be a useful biomarker for PC
GGT activity may serve as a potential surrogate biomarker of atherogenic risk and metabolic health status
High initial GGT concentration and increases in GGT concentration over time should be considered independent predictors of and to have a combined effect on incident metabolic syndrome.
gamma-glutamyltransferase may have a role in nasopharyngeal carcinoma
Formation of LTD4 was rapid when catalyzed by gamma-glutamyl transpeptidase (GGT)1 in the A549 epithelial lung cancer cell line, but considerably slower when catalyzed by GGT5 (show GGT5 ELISA Kits) in primary bronchial epithelial cells. When A549 cells were cultured in the presence of IL-1beta (show IL1B ELISA Kits), GGT1 expression increased about 2-fold. Also exosomes from A549 cells contained GGT1 and augmented LTD4 formation.
Results show a weak genetic evidence that GGT levels may have a causal role in the development of type 2 diabetes.
These findings elucidate a novel mechanism of inflammation-associated osteoclastogenesis, which involves TLR4 (show TLR4 ELISA Kits) recognition of gamma-glutamyltranspeptidase and subsequent activation of MyD88 (show MYD88 ELISA Kits)-dependent signaling.
the present study developed a liver-specific GGT-overexpressing mice model and found that GGT elevation in short term had no effects on glucose metabolism but could increase insulin (show INS ELISA Kits) sensitivity through enhancing the activity of insulin (show INS ELISA Kits) signaling pathway.
Statins can significantly decrease the expression of GGT in aortic atherosclerotic plaques of ApoE (show APOE ELISA Kits)-knockout mice.
Gamma-glutamyltransferase levels are an independent predictor of worsening kidney function and mortality in acute heart failure patients.
Disruption of the Mrds1/Ofcc1 gene elicits asymptomatic hyper-gamma-glutamyl-transpeptidasemia in mice.
Mutations in the Ggt1 gene are responsible for the phenotypes of dwg/dwg and dwg(Bayer)/dwg(Bayer) mice.
prooxidant reactions mediated by gamma-GT in turn regulate the levels of tyrosinase (show TYR ELISA Kits) in pigment cells.
GGT regulates osteoclast biology at least partly independently of sex steroids
GGT stimulates RANKL (show TNFSF11 ELISA Kits) expression
GGT is implicated as being involved in diseases characterized by accelerated osteoclast development and bone destruction.
The enzyme encoded by this gene catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein, and is present in tissues involved in absorption and secretion. This enzyme is a member of the gamma-glutamyltransferase protein family, of which many members have not yet been fully characterized and some of which may represent pseudogenes. This gene is classified as type I gamma-glutamyltransferase. Multiple alternatively spliced variants, encoding the same protein, have been identified.
, gamma-glutamyltranspeptidase 1
, GGT 1
, gamma-glutamyl transpeptidase
, glutathione hydrolase 1
, leukotriene-C4 hydrolase
, glutamyl transpeptidase
, gamma glutamyl-transferase 1
, gamma-glutamyltransferase 2
, ggt 1
, gamma-glutamyltransferase 1 a
, Gamma-glutamyltranspeptidase 1
, gamma-glutamyltranspeptidase 1-like
, Gamma-glutamyltransferase 1