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rho GTPase Activating Protein 8 Proteins (ARHGAP8)

ARHGAP8 encodes a member of the RHOGAP family. Additionally we are shipping rho GTPase Activating Protein 8 Antibodies (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ARHGAP8 23779 P85298
ARHGAP8 73167 Q9CXP4
Rat ARHGAP8 ARHGAP8 300115  
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Top rho GTPase Activating Protein 8 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
$6,570.39
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
$9,371.15
Details
Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg 6 to 10 Days
$302.50
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
$932.80
Details

ARHGAP8 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for rho GTPase Activating Protein 8 (ARHGAP8) Interaction Partners

Human rho GTPase Activating Protein 8 (ARHGAP8) interaction partners

  1. Fusion protein PRR5-ARHGAP8 plays a role in bipolar disorder with binge eating behavior.

  2. BPGAP1 provides a crucial spatiotemporal checkpoint where JNK and MP1/MEK1 work in concert to regulate endosomal and nuclear ERK signaling in cell proliferation control.

  3. Pin1 regulates BPGAP1 function in Rho and Erk signalling, with active Mek2 serving as a novel regulatory scaffold that promotes crosstalk between RhoGAP, Pin1 and Erk in the regulation of cell migration.

  4. BPGAP1 has a role in regulating cell dynamics with BNIP-2 and Cdc42GAP homology/Sec14p-like, proline-rich, and GTPase-activating protein domains of BPGAP1

  5. RhoGAP functionally interacts with cortactin and represents a novel determinant in the regulation of cell dynamics.

  6. ARHGAP8 expression was up-regulated in the majority of primary colorectal tumors analyzed in this work.

  7. BPGAP1 is a novel RhoGAP that co-ordinately regulates pseudopodia and cell migration through the interplay of its BNIP-2 and Cdc42GAP homology domains.

  8. findings reveal a concomitant activation of endocytosis and ERK signaling by BPGAP1 via the coupling of its proline-rich region, which targets EEN and its functional GAP domain

  9. This paper compares the protein sequences and genomic structures of human and mouse ARHGAP8.

rho GTPase Activating Protein 8 (ARHGAP8) Protein Profile

Protein Summary

This gene encodes a member of the RHOGAP family. GAP (GTPase-activating) family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. GAP proteins alternate between an active (GTP-bound) and inactive (GDP-bound) state based on the GTP:GDP ratio in the cell. This family member is a multidomain protein that functions to promote Erk activation and cell motility. Alternative splicing results in multiple transcript variants. Read-through transcripts from the upstream proline rich 5, renal (PRR5) gene into this gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.

Gene names and symbols associated with ARHGAP8

  • Rho GTPase activating protein 8 (ARHGAP8)
  • Rho GTPase activating protein 8 (arhgap8)
  • Rho GTPase activating protein 8 (Arhgap8)
  • 3110043J09Rik protein
  • BPGAP1 protein
  • PP610 protein

Protein level used designations for ARHGAP8

rho GTPase-activating protein 8 , Rho GTPase activating protein 8 , BCH domain-containing Cdc42GAP-like protein , BNIP-2 and Cdc42GAP homology domain-containing, proline-rich and Cdc42GAP-like protein subtype-1 , rho-type GTPase-activating protein 8

GENE ID SPECIES
418239 Gallus gallus
549705 Xenopus (Silurana) tropicalis
100533202 Sus scrofa
100533462 Canis lupus familiaris
100533466 Monodelphis domestica
100601728 Nomascus leucogenys
23779 Homo sapiens
73167 Mus musculus
300115 Rattus norvegicus
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