Browse our Pellino Homolog 1 (Drosophila) Proteins (PELI1)

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1 allowing subsequent NF-kappa-B activation (By similarity).

• pellino E3 ubiquitin protein ligase 1 (PELI1)
• pellino 1 (Peli1)
• pellino E3 ubiquitin protein ligase 1 (Peli1)
• pellino E3 ubiquitin protein ligase 1 S homeolog (peli1.S)
• pellino E3 ubiquitin protein ligase 1b (peli1b)

• 2810468L03Rik protein
• A930031K15Rik protein
• AA409794 protein
• AI586297 protein
• D11Ertd676e protein
• Show all synonym aliases
• peli1 protein
• peli1.L protein
• pellino1 protein
• wu:fd12d01 protein
• xpellino1 protein
• zgc:153297 protein

E3 ubiquitin-protein ligase pellino homolog 1 , pellino homolog 1 , pellino-1 , pellino-related intracellular-signaling molecule , protein pellino homolog 1 , pellino 1 , pellino protein , pellino E3 ubiquitin protein ligase 1 L homeolog , pellino E3 ubiquitin protein ligase 1 S homeolog , pellino homolog 1b