Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
Select your origin of interest
Taken together, these results suggested that alpha1B-adrenoceptor signaling is required for bone formation and regulated cellular proliferation through a mechanism relevant to the up-regulation of CCAAT/enhancer-binding protein delta (show CEBPD Proteins) in osteoblasts and, thus, provide new evidence for the physiological importance of alpha1B-adrenoceptor signalling in bone homeostasis
eIF3f (show EIF3F Proteins)/alpha adrenergic receptor interaction
The adra1b mediates adrenergic vasoconstriction in mouse retinal arterioles with damaged endothelium
in mouse ureters: the mRNA for the alpha1A-adrenoceptor was more prevalent than those for the alpha1B- and alpha1D-adrenoceptors
Overexpression of the alpha(1B (show CACNA1B Proteins))-AR in mice can cause a synucleinopathy with excessive tyrosine nitration but decreased phoshorylation similar to parkinsonian syndromes
alpha(1)-ARs (show SLURP1 Proteins) in male mice are required for the physiological hypertrophy of normal postnatal cardiac development and for an adaptive response to cardiac stress
alpha(1A)- and alpha(1B (show CACNA1B Proteins))-adrenoceptors have roles in myocardial contractions
ADRA1b has a role in regulating glucose homeostasis in mice
These results demonstrate a critical role for the alpha(1B (show CACNA1B Proteins))AR in baroreceptor-mediated adrenergic signaling at the vascular neuroeffector junction. Moreover, alpha(1B (show CACNA1B Proteins))ARs (show SLURP1 Proteins) modulate inotropic responses to baroreceptor activation.
alpha1B-ARs (show SLURP1 Proteins) are the major alpha1-AR subtype expressed in DU145, PC3 (show BTG2 Proteins), and all TRAMP (show DPT Proteins) cell lines, but most of the receptor is localized in intracellular compartments in a nonfunctional state, which can be rescued upon prolonged incubation with any ligand.
Receptor Species-dependent Desensitization Controls KCNQ1 (show KCNQ1 Proteins)/KCNE1 (show KCNE1 Proteins) K+ Channels as Downstream Effectors of Gq Protein-coupled Receptors.(
protein kinase C modulates alpha1B-adrenergic receptor transfer to late endosomes and that Rab9 regulates this process and participates in G protein-mediated signaling turn-off.
alpha1A-adrenergic receptors are stably expressed and stimulate cell migration and TGF-beta1 (show TGFB1 Proteins), IGF-1 (show IGF1 Proteins), hyaluronan and PIP (show PIP Proteins) production in human skin fibroblasts.
heteromeric receptor complexes between alpha1A-AR and CXCR4 (show CXCR4 Proteins) and between alpha1B-AR and CXCR4 (show CXCR4 Proteins) are constitutively expressed in rat and human vascular smooth muscle cells; the quaternary structure of the receptor complex is important for signaling and contraction
alpha1B-AR signals through calcium, ERK1/2 and p38 (show CRK Proteins) only when located in the membrane and the signals disappear by membrane disruption.
A rare ADRA1B haplotype composed of six single nucleotide polymorphism(SNP)s is associated with attention deficit hyperactivity disorder (ADHD).
Noradrenaline facilitated cell proliferation by regulation of potassium currents in human osteoblasts via G(i/o) -protein-coupled alpha(1B (show CACNA1B Proteins)) -adrenoceptors, not via coupling to Gq-proteins
Data show that sphingosine 1-phosphate can induce alpha1B-adrenergic receptor internalization and that its autocrine/paracrine generation is relevant for internalization induced by IGF-I (show IGF1 Proteins).
A-kinase anchoring protein (AKAP)-Lbc anchors a PKN-based signaling complex involved in alpha1-adrenergic receptor-induced p38 activation.
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
, adrenergic, alpha-1B-, receptor
, alpha-1B adrenergic receptor-like
, alpha-1B adrenergic receptor
, alpha-1B adrenoreceptor
, alpha1B-adrenergic receptor
, alpha-1B-adrenergic receptor
, Adrenergic alpha 1B- receptor
, adrenergic receptor, alpha 1b
, alpha 1B-adrenoceptor
, alpha 1B-adrenoreceptor
, alpha 1b adrenoceptor