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This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
serine/threonine protein kinase 11
, serine/threonine kinase 11 (Peutz-Jeghers syndrome)
, Serine/threonine-protein kinase 11
, serine/threonine-protein kinase STK11
, serine/threonine kinase 11
, serine/threonine-protein kinase 11-like
, liver kinase B1
, polarization-related protein LKB1
, renal carcinoma antigen NY-REN-19
, serine/threonine-protein kinase 11
, serine/threonine-protein kinase LKB1
, LKB1 short isoform
, liver kinase B1 homolog
, egg and embryo kinase 1
, serine/threonine-protein kinase XEEK1
, serine/threonine-protein kinase stk11