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CD31 antibody (Platelet/endothelial Cell Adhesion Molecule) (Biotin) Primary Antibody

PECAM1 Reactivity: Human FACS Host: Mouse Monoclonal MEM-05 Biotin
Pubmed (1)
Catalog No. ABIN111925
$387.20
Plus shipping costs $45.00
0.1 mg
local_shipping Shipping to: United States
Available
  • Target
    CD31 (PECAM1)
    Reactivity
    • 346
    • 157
    • 89
    • 73
    • 48
    • 46
    • 22
    • 18
    • 15
    • 8
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 236
    • 160
    • 56
    • 6
    • 3
    • 1
    • 1
    Mouse
    Clonality
    • 327
    • 136
    Monoclonal
    Conjugate
    • 188
    • 44
    • 38
    • 32
    • 17
    • 10
    • 8
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD31 antibody is conjugated to Biotin
    Application
    • 315
    • 197
    • 150
    • 123
    • 80
    • 52
    • 44
    • 42
    • 29
    • 27
    • 26
    • 19
    • 14
    • 13
    • 7
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Immunogen
    Leucocytes of patient suffering from LGL-type leukaemia
    Clone
    MEM-05
    Isotype
    IgG1
  • Application Notes
    Flow cytometry (1/500).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • Soupene, Serikov, Kuypers: "Characterization of an acyl-coenzyme A binding protein predominantly expressed in human primitive progenitor cells." in: Journal of lipid research, Vol. 49, Issue 5, pp. 1103-12, 2008 (PubMed).

  • Target
    CD31 (PECAM1)
    Alternative Name
    CD31 / PECAM1 (PECAM1 Antibody Abstract)
    Synonyms
    CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, endoCAM, C85791, Cd31, Pecam, platelet/endothelial cell adhesion molecule 1, platelet and endothelial cell adhesion molecule 1, pecam1, PECAM1, Pecam1
    Background
    CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in rebulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.Synonyms: End °CAM, GPIIA', PECAM-1, Platelet endothelial cell adhesion molecule
    Gene ID
    9606
    UniProt
    P16284
    Pathways
    Regulation of Actin Filament Polymerization
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