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Gastrin antibody

GAST Reactivity: Human IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN115354
  • Target See all Gastrin (GAST) Antibodies
    Gastrin (GAST)
    Reactivity
    • 64
    • 33
    • 31
    • 6
    • 2
    • 1
    Human
    Host
    • 63
    • 11
    • 2
    Rabbit
    Clonality
    • 65
    • 11
    Polyclonal
    Conjugate
    • 39
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Gastrin antibody is un-conjugated
    Application
    • 49
    • 27
    • 21
    • 14
    • 13
    • 13
    • 13
    • 11
    • 7
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    The antibody is specific against gastrin-containing cells. This antibody reacts with human gastrin I and human gastrin I fragments.
    Cellular Localization: Cytoplasmic
    Purification
    Purified
    Immunogen
    Recombinant Gastrin conjugated to KLH.
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    Discover our top product GAST Primary Antibody
  • Application Notes
    Immunohistochemistry on formalin-fixed paraffin embedded sections: diluted of 1: 50-1: 100 in an ABC method (30 minutes at room temperature)Recommended Positive Control: Stomach
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    containing sodium azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Gastrin (GAST)
    Alternative Name
    Gastrin (GAST Products)
    Background
    Gastrin is mainly known by its first described role as a gastric acid-hormone but the protein also has the ability to promote cellular growth. More recently, gastrin has been suggested to induce leukocyte-endothelial cell interactions and to have a pro-inflammatory effect. Gastrin has two biologically active peptide forms, G34 and G17 and they activate two different receptors: the CCK-1 receptor, which has low affinity for gastrin but high affinity for the related hormone cholecystokinin (CCK), and the CCK-2 receptor, which has high affinity for both gastrin and CCK and mediates the acid-secretory as well as the proliferative effects of gastrin.Synonyms: GAS, GAST
    Gene ID
    2520
    NCBI Accession
    NP_000796
    UniProt
    P01350
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