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ACE2 antibody

ACE2 Reactivity: Human WB, ELISA, FACS Host: Mouse Monoclonal AC18F unconjugated
Catalog No. ABIN1169449
  • Target See all ACE2 Antibodies
    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
    Reactivity
    • 149
    • 54
    • 47
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 137
    • 19
    • 6
    Mouse
    Clonality
    • 117
    • 45
    Monoclonal
    Conjugate
    • 79
    • 18
    • 12
    • 8
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ACE2 antibody is un-conjugated
    Application
    • 129
    • 75
    • 57
    • 36
    • 35
    • 19
    • 17
    • 11
    • 11
    • 10
    • 10
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Specificity
    Recognizes human ACE2.
    Cross-Reactivity
    Human
    Sterility
    0.2 μm filtered
    Immunogen
    Recombinant human ACE2.
    Clone
    AC18F
    Isotype
    IgG1
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
    Preservative
    Without preservative
    Storage
    4 °C,-20 °C
    Storage Comment
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Expiry Date
    12 months
  • Chaouat, Achdout, Kol, Berhani, Roi, Vitner, Melamed, Politi, Zahavy, Brizic, Lenac Rovis, Alfi, Wolf, Jonjic, Israely, Mandelboim: "SARS-CoV-2 receptor binding domain fusion protein efficiently neutralizes virus infection." in: PLoS pathogens, Vol. 17, Issue 12, pp. e1010175, (2022) (PubMed).

    Chaouat, Brizic, Kucan Brlic, Atari, Kliker, Alfi, Mandelboim, Wolf, Tafish, Kol, Jonjic, Mandelboim: "Anti-human ACE2 antibody neutralizes and inhibits virus production of SARS-CoV-2 variants of concern." in: iScience, Vol. 25, Issue 9, pp. 104935, (2022) (PubMed).

    Buchrieser, Dufloo, Hubert, Monel, Planas, Rajah, Planchais, Porrot, Guivel-Benhassine, Van der Werf, Casartelli, Mouquet, Bruel, Schwartz: "Syncytia formation by SARS-CoV-2-infected cells." in: The EMBO journal, pp. e106267, (2020) (PubMed).

    Zulli, Rai, Buxton, Burrell, Hare: "Co-localization of angiotensin-converting enzyme 2-, octomer-4- and CD34-positive cells in rabbit atherosclerotic plaques." in: Experimental physiology, Vol. 93, Issue 5, pp. 564-9, (2008) (PubMed).

  • Target
    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
    Alternative Name
    ACE2 (ACE2 Products)
    Synonyms
    ACE1 antibody, CD143 antibody, DCP antibody, DCP1 antibody, ICH antibody, MVCD3 antibody, ACEH antibody, 2010305L05Rik antibody, zgc:92514 antibody, angiotensin I converting enzyme antibody, angiotensin I converting enzyme 2 antibody, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 antibody, ACE antibody, ACE2 antibody, Ace2 antibody, ace2 antibody
    Background
    ACE2 has direct effects on cardiac functions. It is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE2 converts angiotensin I to angiotensin 1-9. ACE2 was also identified as a functional receptor for SARS coronavirus.
    UniProt
    Q9BYF1
    Pathways
    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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