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SATB2 antibody (SATB Homeobox 2) AA 451-485 (FITC) Primary Antibody

SATB2 Reactivity: Human, Mouse, Rat FACS, IF (cc), IF (p) Host: Rabbit Polyclonal FITC
Catalog No. ABIN1394270
$476.30
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 11 to 16 Business Days
  • Target See all SATB2 Antibodies
    SATB2
    Binding Specificity
    • 15
    • 9
    • 8
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 451-485
    Reactivity
    • 59
    • 34
    • 30
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 52
    • 7
    Rabbit
    Clonality
    • 44
    • 15
    Polyclonal
    Conjugate
    • 26
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SATB2 antibody is conjugated to FITC
    Application
    • 39
    • 22
    • 15
    • 13
    • 13
    • 11
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Cow,Sheep,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SATB2
    Isotype
    IgG
  • Application Notes
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C/-80 °C
    Storage Comment
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Expiry Date
    12 months
  • Target
    SATB2
    Alternative Name
    SATB2 (SATB2 Products)
    Synonyms
    RGD1562369, mKIAA1034, SATB homeobox 2, special AT-rich sequence binding protein 2, SATB2, satb2, Satb2
    Background

    Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating BCL11B expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation.

    Subcellular location: Nucleus

    Synonyms: GLSS, DNA-binding protein SATB2, Special AT-rich sequence-binding protein 2, SATB2, KIAA1034

    Gene ID
    UniProt
    Q9UPW6
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