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UBE2D2 antibody (Ubiquitin-Conjugating Enzyme E2D 2) AA 31-130 (Alexa Fluor 488) Primary Antibody

UBE2D2 Reactivity: Human, Mouse IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 488
Catalog No. ABIN1398556
$476.30
Plus shipping costs $45.00
100 μL
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  • Target See all UBE2D2 Antibodies
    UBE2D2
    Binding Specificity
    • 14
    • 13
    • 10
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-130
    Reactivity
    • 68
    • 34
    • 19
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 57
    • 11
    Rabbit
    Clonality
    • 58
    • 10
    Polyclonal
    Conjugate
    • 38
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBE2D2 antibody is conjugated to Alexa Fluor 488
    Application
    • 51
    • 27
    • 12
    • 12
    • 12
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Rat,Cow,Sheep,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human UBE2D2
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C/-80 °C
    Storage Comment
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Expiry Date
    12 months
  • Target
    UBE2D2
    Alternative Name
    UBE2D2 (UBE2D2 Products)
    Synonyms
    E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH5B, 1500034D03Rik, Ubc2e, Ube2d2, ubc4, ube2d2, zgc:55886, E217kB, ubiquitin conjugating enzyme E2 D2, ubiquitin-conjugating enzyme E2D 2A, ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast), ubiquitin-conjugating enzyme E2D 2, ubiquitin conjugating enzyme E2 D3, UBE2D2, Ube2d2a, ube2d2, Ube2d2, UBE2D3
    Background

    Ubiquitin is an abundant, highly conserved protein found in all eukaryotic cells either free or covalently attached to cellular proteins. The primary function of ubiquitin in mammalian systems is to clear abnormal, foreign, and improperly folded proteins by targeting them for proteosome degradation. UBE2D proteins, including UBE2D1 (ubiquitin-conjugating enzyme E2D1 or UBC5A), UBE2D2 (ubiquitin-conjugating enzyme E2D2 or UBC5B) and UBE2D3 (ubiquitin-conjugating enzyme E2D3 or UBC5C), are E2 ubiquitin-conjugating enzymes that catalyze the ubiquitination of I˚,Bå, in a phosphorylation and SCFB-TRCP-dependent manner. Specifically, E1 first transfers a ubiquitin residue to the E2 component (a UBE2D protein), and the UBE2D protein then associates with an E3 ubiquitin-protein ligase, which immediately transfers that residue to a protein that is targeted for degradation.

    Subcellular location: Cytoplasm, Nucleus, Secreted, Extracellular matrix

    Synonyms: PUBC 1, PUBC1, UB2D2_HUMAN, UBC 4, UBC 4/5, UBC4, UBC4/5, UBC4/5 homolog yeast, UBCH 5B, UBCH5B, UBE2D2, Ubiquitin carrier protein, Ubiquitin carrier protein D2, Ubiquitin conjugating enzyme E2 17 kDa 2, Ubiquitin conjugating enzyme E2 D2, Ubiquitin conjugating enzyme E2D 2 homologous to yeast UBC4/5, Ubiquitin conjugating enzyme E2D 2 UBC4/5 homolog yeast, Ubiquitin conjugating enzyme E2D 2, Ubiquitin protein ligase D2, Ubiquitin-conjugating enzyme E2 D2, Ubiquitin-conjugating enzyme E217KB 2, Ubiquitin-conjugating enzyme E2-17 kDa 2, Ubiquitin-protein ligase D2, E217KB2.

    Gene ID
    Pathways
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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