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SERPINB3 + SERPINB4 antibody (Alexa Fluor 488) Primary Antibody

Reactivity: Human IF (p) Host: Rabbit Polyclonal Alexa Fluor 488
Catalog No. ABIN1401502
$476.30
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 11 to 16 Business Days
  • Target
    SERPINB3 + SERPINB4
    Reactivity
    Human
    Host
    • 14
    Rabbit
    Clonality
    • 14
    Polyclonal
    Conjugate
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Alexa Fluor 488
    Application
    • 12
    • 3
    • 3
    Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SERPINB3 (same as SERPINB4)
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C/-80 °C
    Storage Comment
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Expiry Date
    12 months
  • Target
    SERPINB3 + SERPINB4
    Synonyms
    HsT1196, SCC, SCCA-1, SCCA-PD, SCCA1, T4-A, serpin family B member 3, SERPINB3
    Background

    Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins. Among the proteins mediating metastasis are serine prote-ases, such as neutrophil elastase.SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1. The human SCCA1 gene encodes a 390 amino acid protein that was originally isolated from a metastatic cervical squamous cell carcinoma. SCCA2 may act as a protease inhibitor to modulate the host immune response against tumor cells.

    Synonyms: HsT1196, Protein T4 A, Protein T4-A, SCC, SCCA PD, SCCA-1, SCCA1, SCCAPD, Serine or cysteine proteinase inhibitor clade B ovalbumin member 3, Serpin B3, Serpin peptidase inhibitor clade B ovalbumin member 3, SERPINB3, SPB3_HUMAN, Squamous cell carcinoma antigen 1, T4 A, T4A, SCCA 2, SCCA2, Leupin, Peptidase inhibitor 11, PI 11, PI-11, PI11, Protease inhibitor leucine serpin, SCCA-2, SCCA1, SCCA2/SCCA1 fusion protein, Serine or cysteine proteinase inhibitor, clade B ovalbumin, member 4, Serpin B4, Serpin peptidase inhibitor, clade B ovalbumin, member 4, SERPINB 4, SERPINB4, SPB4_HUMAN, Squamous cell carcinoma antigen 1, Squamous cell carcinoma antigen 2.

    Gene ID
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