GBA2 antibody (Glucosidase, beta (Bile Acid) 2) (AA 630-680) (Cy7)

Details for Product anti-GBA2 Antibody No. ABIN1708073
Target
Binding Specificity
AA 630-680
14
4
2
2
2
1
1
1
Reactivity
Human, Mouse, Rat
38
27
24
Host
Rabbit
37
2
Clonality
Polyclonal
Conjugate
This GBA2 antibody is conjugated to Cy7
3
2
2
2
2
2
2
2
2
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
18
12
11
5
4
3
1
1
1
1
Options
Immunogen KLH conjugated synthetic peptide derived from human GBA2
Isotype IgG
Purification Purified by Protein A.
Target
Alternative Name GBA2 (GBA2 Antibody Abstract)
Background

Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide (GlcCer) to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation. May also catalyze the hydrolysis of bile acid 3-O-glucosides, however, the relevance of such activity is unclear in vivo. Plays a role in central nevous system development. Required for proper formation of motor neuron axons.

Subcellular location: Intracellular

Synonyms: AD035, SPG46, NLGase, Non-lysosomal glucosylceramidase, Beta-glucocerebrosidase 2, Beta-glucosidase 2, Glucosylceramidase 2, GBA2, KIAA1605
Gene ID 57704
UniProt Q9HCG7
Application Notes IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months