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SCUBE3 antibody (AA 451-550) (Cy7)

SCUBE3 Reactivity: Human IF (cc), IF (p) Host: Rabbit Polyclonal Cy7
Catalog No. ABIN1708758
  • Target See all SCUBE3 Antibodies
    SCUBE3 (Signal Peptide, CUB Domain, EGF-Like 3 (SCUBE3))
    Binding Specificity
    • 14
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 451-550
    Reactivity
    • 31
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 28
    • 3
    Rabbit
    Clonality
    • 29
    • 2
    Polyclonal
    Conjugate
    • 13
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SCUBE3 antibody is conjugated to Cy7
    Application
    • 16
    • 15
    • 12
    • 12
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SCUBE3
    Isotype
    IgG
    Top Product
    Discover our top product SCUBE3 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    SCUBE3 (Signal Peptide, CUB Domain, EGF-Like 3 (SCUBE3))
    Alternative Name
    SCUBE3 (SCUBE3 Products)
    Synonyms
    CEGF3 antibody, D030038I21Rik antibody, signal peptide, CUB domain and EGF like domain containing 3 antibody, signal peptide, CUB domain, EGF-like 3 antibody, signal peptide, CUB and EGF-like domain-containing protein 3 antibody, SCUBE3 antibody, scube3 antibody, Scube3 antibody, LOC100152993 antibody
    Background

    Synonyms: CEGF3, CUB and EGF containing protein 3, CUB and EGF-like domain-containing protein 3, CUB domain and EGF like repeat containing 3, DKFZp686B09105, DKFZp686B1223, DKFZp686D20108, FLJ34743, OTTHUMP00000016250, SCUB3_HUMAN, SCUBE 3, SCUBE3, Signal peptide, Signal peptide CUB and EGF like domain containing protein 3, Signal peptide CUB domain EGF like 3.

    Background: SCUBE3 is a novel secreted 993 amino acid cell-surface osteoblast protein that plays an important role in bone cell biology. While highly expressed in osteoblasts, SCUBE3 expression is unobservable or very low in non-bone tissues. SCUBE3 forms homo-oligomers and hetero-oligomers with SCUBE1, and may undergo C-terminal proteolytic cleavage or become N-glycosylated following translation. Two SCUBE3 isoforms exist as a result of alternative splicing events. SCUBE3 contains one CUB domain and nine EGF-like domains, and is encoded by a gene which maps to human chromosome 6p21.31, a region associated with a rare form of metabolic bone disease known as Paget's disease. Chromosome 6 contains 170 million base pairs and comprises nearly 6 % of the human genome.

    Gene ID
    222663
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