PTGER4 antibody (AA 242-269)

Catalog No. ABIN1881704

Product Details anti-PTGER4 Antibody

Target: PTGER4 (Prostaglandin E Receptor 4 (Subtype EP4) (PTGER4))

Binding Specificity: AA 242-269

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGER4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: B, Rb, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PTGER4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-269 amino acids from the Central region of human PTGER4.

Clone: RB44208

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-PTGER4 antibody (ABIN1881704)

Mori, Tanaka, Kotani, Miyaoka, Sando, Muro, Sasaki, Nakagawa, Ogawa, Usui, Ozaki, Ichikawa, Narumiya, Nakao: "Gene expression of the human prostaglandin E receptor EP4 subtype: differential regulation in monocytoid and lymphoid lineage cells by phorbol ester." in: Journal of molecular medicine (Berlin, Germany), Vol. 74, Issue 6, pp. 333-6, (1996) (PubMed).

Foord, Marks, Stolz, Bufflier, Fraser, Lee: "The structure of the prostaglandin EP4 receptor gene and related pseudogenes." in: Genomics, Vol. 35, Issue 1, pp. 182-8, (1996) (PubMed).

Bastien, Sawyer, Grygorczyk, Metters, Adam: "Cloning, functional expression, and characterization of the human prostaglandin E2 receptor EP2 subtype." in: The Journal of biological chemistry, Vol. 269, Issue 16, pp. 11873-7, (1994) (PubMed).

An, Yang, Xia, Goetzl: "Cloning and expression of the EP2 subtype of human receptors for prostaglandin E2." in: Biochemical and biophysical research communications, Vol. 197, Issue 1, pp. 263-70, (1994) (PubMed).

Target Details for PTGER4

Target: PTGER4 (Prostaglandin E Receptor 4 (Subtype EP4) (PTGER4))

Alternative Name: PTGER4 (PTGER4 Products)

Background: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

Molecular Weight: 53119

NCBI Accession: NP_000949

UniProt: P35408