CXXC Finger Protein 4 (CXXC4) antibody

Details for Product No. ABIN2668013
Antigen
Reactivity
Human, Mouse (Murine)
40
17
7
2
2
2
2
2
1
1
Host
Rabbit
33
7
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
3
3
3
Application
Western Blotting (WB)
31
28
25
15
5
3
1
1
Options
Isotype IgG
Purification Affinity Purified
Antigen
Alternative Name Cxxc4 (CXXC4 Antibody Abstract)
Background Cxxc4 (CXXC Finger Protein 4) acts as a negative regulator of the Wnt signaling pathway via its interaction with DVL1 and has been implicated in malignant renal cell carcinoma and colonic villous adenoma. Recently, Cxxc4 has been shown to be involved in the regulation of DNA demethylation. It binds to unmethylated CpGs in DNA and is involved in TET2 downregulation.
Molecular Weight 42 kDa
Gene ID 319478
Application Notes Validated Applications: WB: 1:1,000 - 1:2,500 dilution The addition of 0.1 % Tween 20 in the blocking buffer and primary antibody incubation buffer is recommended to aid in detection by Western blot. Individual optimization may be required.
Restrictions For Research Use only
Format Liquid
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice

Avoid repeated freeze/thaw cycles and keep on ice when not in storage. This product is guaranteed for 6 months from date of receipt.

Storage -20 °C
Storage Comment Antibodies in solution can be stored at -20°C for 2 years.
Expiry Date 6 months