CD33 antibody (CD33 Molecule)

Details for Product anti-CD33 Antibody No. ABIN2689194
Antigen
  • SIGLEC-3
  • SIGLEC3
  • p67
  • Siglec-3
  • gp67
  • CD33 molecule
  • CD33 antigen
  • CD33
  • Cd33
Reactivity
Human
492
50
39
22
8
7
4
2
1
Host
Mouse
367
148
1
1
1
Clonality (Clone)
Monoclonal ()
Conjugate
This CD33 antibody is un-conjugated
59
53
35
23
12
10
7
6
6
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
327
194
120
105
88
52
28
26
24
19
19
17
12
6
6
5
3
2
2
1
Options
Brand BD Pharmingen™
Clone WM53
Isotype IgG1, kappa
Characteristics Reacts with a 67 kDa type I transmembrane glycoprotein expressed on monocytes, activated T cells, myeloid progenitors as well as mast cells. CD33 is absent on normal platelets, lymphocytes, erythrocytes, and hematopoietic stem cells. Reports indicate that this glycoprotein can function as a sialic acid-dependent cell adhesion molecule and this function can be modulated by endogenous sialoglycoconjugates when CD33 is expressed on the membrane. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood granulocytes analyzed on a FACScan Profile of peripheral blood monocytes analyzed on a FACScan

BD Pharmingen™ Purified Mouse Anti-Human CD33 - Purified - Clone WM53 (also known as WM-53) - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Plasmids, Primers & others Plasmids, Primers & others CD33 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name CD33 (CD33 Antibody Abstract)
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Aqueous buffered solution containing ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store undiluted at 4°C.
Product cited in: Freeman, Kelm, Barber, Crocker: "Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules." in: Blood, Vol. 85, Issue 8, pp. 2005-12, 1995 (PubMed).

Nakamura, Noma, Kidokoro, Kobayashi, Takei, Kurashima, Mukaiyama, Kato: "Expression of CD33 antigen on normal human activated T lymphocytes." in: Blood, Vol. 83, Issue 5, pp. 1442-3, 1994 (PubMed).

Favaloro, Moraitis, Koutts, Exner, Bradstock: "Endothelial cells and normal circulating haemopoietic cells share a number of surface antigens." in: Thrombosis and haemostasis, Vol. 61, Issue 2, pp. 217-24, 1989 (PubMed).