SEC63 antibody (SEC63 Homolog (S. Cerevisiae)) (C-Term)

Details for Product anti-SEC63 Antibody No. ABIN2773888
Antigen
  • DNAJC23
  • ERdj2
  • PRO2507
  • SEC63L
  • 5730478J10Rik
  • AI649014
  • AW319215
  • SEC63-like
  • zgc:92718
  • SEC63 homolog, protein translocation regulator
  • SEC63-like (S. cerevisiae)
  • SEC63 homolog, protein translocation regulator L homeolog
  • SEC63
  • Sec63
  • sec63
  • sec63.L
Epitope
C-Term
10
9
8
2
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish (Danio rerio)
32
10
8
4
3
3
3
2
2
2
2
1
1
Host
Rabbit
28
4
Clonality
Polyclonal
Conjugate
This SEC63 antibody is un-conjugated
2
2
2
2
2
2
Application
Western Blotting (WB)
32
21
16
3
1
Options
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human SEC63
Sequence WWLYIADRKE QTLISMPYHV CTLKDTEEVE LKFPAPGKPG NYQYTVFLRS
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
Characteristics This is a rabbit polyclonal antibody against SEC63. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Plasmids, Primers & others Plasmids, Primers & others SEC63 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name SEC63 (SEC63 Antibody Abstract)
Background The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. SEC63 and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. SEC63 is an integral membrane protein located in the rough ER.The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.
Alias Symbols: ERdj2, PRO2507, SEC63L, DNAJC23
Protein Interaction Partner: UBC, IRF1, SEC61B, SEC62, GSTK1,
Protein Size: 760
Molecular Weight 88 kDa
Gene ID 11231
NCBI Accession NM_007214, NP_009145
UniProt Q9UGP8
Pathways ER-Nucleus Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 760 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Image no. 1 for anti-SEC63 Homolog (S. Cerevisiae) (SEC63) (C-Term) antibody (ABIN2773888) WB Suggested Anti-SEC63 Antibody Titration: 1.25ug/ml Positive Control: HepG2 cell...
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