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NR2F2 antibody (Nuclear Receptor Subfamily 2, Group F, Member 2) (N-Term) Primary Antibody

NR2F2 Reactivity: Human, Mouse, Dog, Pig, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2774661
$389.00
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100 μL
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  • Target
    NR2F2
    Binding Specificity
    N-Term
    • 19
    • 16
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Reactivity
    Human, Mouse, Dog, Pig, Rabbit
    • 56
    • 25
    • 23
    • 12
    • 9
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    Host
    Rabbit
    Clonality
    Polyclonal
    Conjugate
    This NR2F2 antibody is un-conjugated
    • 34
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Application
    Western Blotting (WB)
    • 41
    • 31
    • 12
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Sequence
    AMVVSTWRDP QDEVPGSQGS QASQAPPVPG PPPGAPHTPQ TPGQGGPAST
    Cross-Reactivity
    Cow (Bovine), Dog (Canine), Chicken, Human, Mouse (Murine), Rat (Rattus)
    Predicted Reactivity
    Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%
    Characteristics
    This is a rabbit polyclonal antibody against NR2F2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human NR2F2
  • Application Notes
    WB Suggested Anti-NR2F2 Antibody Titration: 0.2-1 µg/mL
    ELISA Titer: 1:62500
    Positive Control: Human brain.
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 414 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    NR2F2
    Alternative Name
    NR2F2 (NR2F2 Antibody Abstract)
    Synonyms
    nr2f2, MGC52954, ARP1, COUPTFB, COUPTFII, NF-E3, NR2F1, SVP40, TFCOUP2, 2700033K02Rik, 9430015G03Rik, ARP-1, Aporp1, COUP-TF2, COUP-TFII, EAR3, Tcfcoup2, Tfcoup2, fc94g08, svp40, svp[40], wu:fc94g08, nuclear receptor subfamily 2 group F member 2 L homeolog, Nr2f2 protein, nuclear receptor subfamily 2 group F member 2, nuclear receptor subfamily 2, group F, member 2, nr2f2.L, nr2f2, NR2F2, Nr2f2
    Background
    NR2F2, an orphan member of the nuclear hormone receptor superfamily, acts as a transcriptional repressor by antagonizing the functions of other nuclear hormone receptors and by actively silencing transcription. However, in certain contexts, NR2F2 stimulates transcription directly. NR2F2, MyoD and p300 interact in a competitive manner, and that increasing amounts of NR2F2 have the ability to reduce the interaction between myoD and p300 invitro. NR2F2 post-transcriptionally regulates myoD activity/function, and that crosstalk between orphan nuclear receptors and the myogenic bHLH proteins has functional consequences for differentiation.
    Alias Symbols: ARP1, COUP-TFII, COUPTFB, MGC117452, SVP40, TFCOUP2, NF-E3, NR2F1, COUPTFII
    Protein Interaction Partner: NSD1, BCL11A, NR2F2, BIK, SETD7, FAM46A, HIPK3, UBC, TFAP4, Cebpb, SMARCAD1, NR2F6, POU5F1, NR3C1, PHB2, TRIP4, PIAS1, BCL11B, TRIM24, EP300, SQSTM1, HDAC1, NCOR2, MYOD1, LCK,
    Protein Size: 414
    Molecular Weight
    45 kDa
    Gene ID
    7026
    NCBI Accession
    NM_021005, NP_066285
    UniProt
    P24468
    Pathways
    Steroid Hormone Mediated Signaling Pathway
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